rho:Quickview: Difference between revisions

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{|   id="D49b0228a6fa90" class=" tableEdit New_Quickview_Table"


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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[rho:Gene|''rho]]'' (synonyms: ''ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA'')<ref name='LIB:Riley_2006'/>
''rho''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[rho:Gene_Product(s)|Rho product]]<ref name='LIB:Riley_2006'/>: transcription termination factor product, B3783 product, RnsC product, Tsu product, Sun product, NusD product, Psu product, SbaA product, PsuA product, NitA product
''ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA''<ref name='LIB:Riley_2006'/>, hdf, tabC''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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transcription termination factor Rho monomer;  polarity suppressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
transcription termination factor Rho;  polarity suppressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:transcription termination factor Rho|transcription termination factor Rho]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:transcription termination factor Rho|transcription termination factor Rho]]<ref name='LIB:EcoCyc11.1'/>


Transcription termination factor Rho; bicyclomycin target<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''transcription termination factor<ref name='LIB:Riley_2006'/>, B3783<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RnsC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Tsu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Sun<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NusD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Psu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsuA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NitA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Rho<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:rhoL|rhoL]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:rhoL-rho|rhoL-rho]]<ref name='LIB:EcoCyc10.6'/>, rho  
transcription unit(s): [[:Category:Txn_unit:rhoL|rhoL]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:rhoL-rho|rhoL-rho]]<ref name='LIB:EcoCyc10.6'/>, rho  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=rho&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10845]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000836&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=rho&loc=MG1655%3A3964440..3965699,W3110%3A3670264..3669005,REL606%3A3928217..3929476,DH10B%3A4063360..4064619,BW2952%3A3854109..3855368]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3854109&end=3855368&gene=rho&aa=mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqdgfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevnfdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivappkagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrffgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=rho+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=rho]]&nbsp;&nbsp;


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===Notes===
===Notes===
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The ''rho'' gene is often misannotated as a polarity suppressor.  Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/>  Wild type ''rho'' is the source of polarity.
* The ''rho'' gene is often misannotated as a polarity suppressor.  Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/>  Wild type ''rho'' is the source of polarity.
 
* ''rho'' has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/>
rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/>
* ''rho'' is required to maintain genomic integrity by resolving transcription/replication conflicts <ref name='PMID:21183718'/>
 
 
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==References==
==References==

Latest revision as of 21:55, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

rho

Gene Synonym(s)

ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA[1], hdf, tabC

Product Desc.

transcription termination factor Rho; polarity suppressor[2][3];

Component of transcription termination factor Rho[3]

Transcription termination factor Rho; bicyclomycin target[4]

Product Synonyms(s)

transcription termination factor[1], B3783[2][1], RnsC[2][1], Tsu[2][1], Sun[2][1], NusD[2][1], Psu[2][1], SbaA[2][1], PsuA[2][1], NitA[2][1], Rho[2][1] , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rhoL[2], rhoL-rho[2], rho

Regulation/Activity
Quick Links



        

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Notes

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  • The rho gene is often misannotated as a polarity suppressor. Mutations in rho suppress polarity.[5][6][7][8][9] Wild type rho is the source of polarity.
  • rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).[4]
  • rho is required to maintain genomic integrity by resolving transcription/replication conflicts [10]

References

[back to top]


  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Das, A et al. (1976) Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc. Natl. Acad. Sci. U.S.A. 73 1959-63 PubMed
  6. ↑ Korn, LJ & Yanofsky, C (1976) Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J. Mol. Biol. 106 231-41 PubMed
  7. ↑ Belfort, M & Oppenheim, AB (1976) Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant. Mol. Gen. Genet. 148 171-3 PubMed
  8. ↑ Richardson, JP & Carey, JL 3rd (1982) rho Factors from polarity suppressor mutants with defects in their RNA interactions. J. Biol. Chem. 257 5767-71 PubMed
  9. ↑ Das, A et al. (1978) Interaction of RNA polymerase and rho in transcription termination: coupled ATPase. Proc. Natl. Acad. Sci. U.S.A. 75 4828-32 PubMed
  10. ↑ Washburn, RS & Gottesman, ME (2011) Transcription termination maintains chromosome integrity. Proc. Natl. Acad. Sci. U.S.A. 108 792-7 PubMed
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