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{{Tab On|Quickview|hns}}{{Tab|Gene|hns}}{{Tab|Gene Product(s)|hns}}{{Tab|Expression|hns}}{{Tab|Evolution|hns}}{{Tab|On One Page|hns}}{{TabsBottom}}
{{Tab On|Quickview|hns}}{{Tab|Gene|hns}}{{Tab|Gene Product(s)|hns}}{{Tab|Expression|hns}}{{Tab|Evolution|hns}}{{Tab|On One Page|hns}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[hns:Gene|''hns]]'' (synonyms: ''ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, fimG, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1'')<ref name='LIB:Riley_2006'/>
''hns''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[hns:Gene_Product(s)|Hns product]]<ref name='LIB:Riley_2006'/>: global DNA-binding transcriptional dual regulator H-NS<ref name='LIB:Riley_2006'/>, B1237<ref name='LIB:EcoCyc10.6'/>, Irk<ref name='LIB:EcoCyc10.6'/>, MsyA<ref name='LIB:EcoCyc10.6'/>, PilG<ref name='LIB:EcoCyc10.6'/>, TopS<ref name='LIB:EcoCyc10.6'/>, TopX<ref name='LIB:EcoCyc10.6'/>, VirR<ref name='LIB:EcoCyc10.6'/>, Drs<ref name='LIB:EcoCyc10.6'/>, Drc<ref name='LIB:EcoCyc10.6'/>, Cur<ref name='LIB:EcoCyc10.6'/>, Hns<ref name='LIB:EcoCyc10.6'/>, FimG<ref name='LIB:EcoCyc10.6'/>, DrdX<ref name='LIB:EcoCyc10.6'/>, BglY<ref name='LIB:EcoCyc10.6'/>, HnsA<ref name='LIB:EcoCyc10.6'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator<ref name='LIB:EcoCyc10.6'/>, OsmZ<ref name='LIB:EcoCyc10.6'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS)<ref name='LIB:EcoCyc11.1'/>
''ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1''<ref name='LIB:Riley_2006'/>, fimG, H1, verA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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H-NS transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
H-NS transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
DNA-binding global regulator H-NS; diverse mutant phenotypes affecting transcription, transposition, inversion, cryptic-gene expression; involved in chromosome organization; preferentially binds bent DNA; has N-terminal dimerization domain<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''global DNA-binding transcriptional dual regulator H-NS<ref name='LIB:Riley_2006'/>, B1237<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Irk<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsyA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PilG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, VirR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cur<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hns<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DrdX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BglY<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HnsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, OsmZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS)<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/> , B1, bglY, cur, drc, drdX, drs, ECK1232, fimG, H1, hnsA, irk, JW1225, msyA, osmZ, pilG, topS, topX, verA, virR, b1237''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:hns|hns]]<ref name='LIB:EcoCyc10.6'/>, OP00190  
transcription unit(s): [[:Category:Txn_unit:hns|hns]]<ref name='LIB:EcoCyc10.6'/>, OP00190  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=hns&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10457]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000450&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=hns&loc=MG1655%3A1292145..1291732,W3110%3A1294499..1294086,DH10B%3A1332386..1331973,REL606%3A1292716..1292303,BW2952%3A1181230..1181643]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1181230&end=1181643&gene=hns&aa=msealkilnnirtlraqarectletleemleklevvvnerreeesaaaaeveertrklqqyremliadgidpnellnslaavksgtkakraqrpakysyvdengetktwtgqgrtpavikkamdeqgkslddflikq]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hns+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=hns]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
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HN-S forms heteromeric complexes with Hha and Cnu, which modulates HN-S function, expression and stability. Mutations affect chromosomal supercoiling. HT_Cmplx32_Mem: CspC+Hns+HupA.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

hns

Gene Synonym(s)

ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1[1], fimG, H1, verA

Product Desc.

H-NS transcriptional dual regulator[2][3]

DNA-binding global regulator H-NS; diverse mutant phenotypes affecting transcription, transposition, inversion, cryptic-gene expression; involved in chromosome organization; preferentially binds bent DNA; has N-terminal dimerization domain[4]

Product Synonyms(s)

global DNA-binding transcriptional dual regulator H-NS[1], B1237[2][1], Irk[2][1], MsyA[2][1], PilG[2][1], TopS[2][1], TopX[2][1], VirR[2][1], Drs[2][1], Drc[2][1], Cur[2][1], Hns[2][1], DrdX[2][1], BglY[2][1], HnsA[2][1], DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator[2][1], OsmZ[2][1], DNA-binding protein HLP-II (HU, BH2, HD, NS)[3][1] , B1, bglY, cur, drc, drdX, drs, ECK1232, fimG, H1, hnsA, irk, JW1225, msyA, osmZ, pilG, topS, topX, verA, virR, b1237

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hns[2], OP00190

Regulation/Activity
Quick Links



        

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Notes

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HN-S forms heteromeric complexes with Hha and Cnu, which modulates HN-S function, expression and stability. Mutations affect chromosomal supercoiling. HT_Cmplx32_Mem: CspC+Hns+HupA.[4]



References

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  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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