Phage lambda cII:Gene Product(s): Difference between revisions
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<noinclude>{{TabsTop}} | <noinclude>{{TabsTop}} | ||
{{Tab|Quickview|Phage lambda cII}}{{Tab|Gene|Phage lambda cII}}{{Tab On|Gene Product(s)|Phage lambda cII}}{{Tab|Expression|Phage lambda cII}}{{Tab|Evolution|Phage lambda cII}}{{Tab|On One Page|Phage lambda cII}}{{TabsBottom}} | {{Tab|Quickview|Phage lambda cII}}{{Tab|Gene|Phage lambda cII}}{{Tab On|Gene Product(s)|Phage lambda cII}}{{Tab|Expression|Phage lambda cII}}{{Tab|Evolution|Phage lambda cII}}{{Tab|On One Page|Phage lambda cII}}{{TabsBottom}} | ||
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|{{Sub}}[[#Localization |Localization]] | |{{Sub}}[[#Localization |Localization]] | ||
|{{Sub}}[[#Sequence|Sequence]] | |{{Sub}}[[#Sequence|Sequence]] | ||
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]] | |||
|{{Sub}}[[#Structure|Structure]] | |{{Sub}}[[#Structure|Structure]] | ||
|{{Sub}}[[#Gene Product Resources|Resources]] | |{{Sub}}[[#Gene Product Resources|Resources]] | ||
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==Nomenclature== | ==Nomenclature== | ||
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|- | |- | ||
!{{table heading style}} |Standard name | !align=left {{table heading style}} |Standard name | ||
| | || | ||
cII | |||
| | |||
cII | |||
|- | |- | ||
!{{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
| | || | ||
cII, lambdap59 | |||
| | |||
cII, lambdap59 | |||
|- | |- | ||
!{{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
| | || | ||
activator of Pre and Pi | |||
| | |||
|- | |- | ||
!{{table heading style}} |EC number (for enzymes) | !align=left {{table heading style}} |EC number (for enzymes) | ||
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<protect><!--Nomenclature_notes--></protect> | <protect><!--Nomenclature_notes--></protect> | ||
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==Function== | ==Function== | ||
{{BacktoTop}} | |||
<protect> | <protect> | ||
<big>'''Gene Ontology'''</big> | |||
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|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!Qualifier!!GO ID!!GO term name!!Reference | !|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
|-class= | |- | ||
|[{{SERVER}} | | | ||
| | |||
GO:0019044 | |||
| | |||
maintenance of viral latency | |||
| | |||
PMID:9324241 | |||
| | |||
IMP: Inferred from Mutant Phenotype | |||
| | |||
| | |||
P | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0019043 | |||
| | |||
establishment of viral latency | |||
| | |||
PMID:12397182 | |||
| | |||
IMP: Inferred from Mutant Phenotype | |||
| | |||
| | |||
P | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0045893 | |||
| | |||
positive regulation of transcription, DNA-dependent | |||
| | |||
PMID:2931430 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
P | |||
| | |||
| | |||
complete | |||
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{{Product_GO_help}} | {{Product_GO_help}} | ||
{{Product_interactions_help}} | <span id="Interactions"></span><big>'''Interactions '''</big> | ||
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!|Partner Type!!Partner!!Notes!!References!!Evidence | |||
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<!--Function_notes--> | |||
===Notes=== | ===Notes=== | ||
==Localization== | ==Localization== | ||
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!Compartment!!Description!!Evidence!!Notes | !|Compartment!!Description!!Evidence!!Reference/Source!!Notes | ||
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<protect><!--Localization_notes--></protect> | <protect><!--Localization_notes--></protect> | ||
===Notes=== | ===Notes=== | ||
==Structure and Physical Properties== | ==Structure and Physical Properties== | ||
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<protect> | <protect> | ||
= | <span id="Sequence"></span><big>'''Physical Properties'''</big> | ||
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{| class=" tableEdit Product_phys_prop_table" | |||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |Name | ||
| | || | ||
|- | |||
!align=left {{table heading style}} |Sequence | |||
|| | |||
<pre>MVRANKRNEA LRIESALLNK IAMLGTEKTA EAVGVDKSQI SRWKRDWIPK FSMLLAVLEW | <pre>MVRANKRNEA LRIESALLNK IAMLGTEKTA EAVGVDKSQI SRWKRDWIPK FSMLLAVLEW | ||
GVVDDDMARL ARQVAAILTN KKRPAATERS EQIQMEF</pre> | GVVDDDMARL ARQVAAILTN KKRPAATERS EQIQMEF</pre> | ||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |Length | ||
| | || | ||
97 | |||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |Mol. Wt | ||
| | || | ||
11.055 kDa | |||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |pI | ||
| | || | ||
10.1 (calculated) | |||
|- | |- | ||
| | !align=left {{table heading style}} |Extinction coefficient | ||
|| | |||
16,500 (calc based on 0 Y, 3 W, and 0 C residues) | |||
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= | |||
<!--box uid=421aa90e079fa326b6494f812ad13e79..L46a41629dbd14--> | <span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table> | ||
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!Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes!!References | ||
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{{Product_domains_motifs_help}} | {{Product_domains_motifs_help}}</td> | ||
== | <td> | ||
<!-- motifs column 2--> | |||
<motif_map/> | |||
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</table> | |||
<table><tr valign='top'><td> | |||
<span id='Structure'></span><big>'''Structure'''</big><br /> | |||
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!align=left {{table heading style}} |Structures | |||
|| | |||
<beststructure> | |||
gene=Phage_lambda_cII | |||
taxon=10710 | |||
</beststructure> | |||
|- | |||
!align=left {{table heading style}} |Models | |||
|| | |||
View models at: | |||
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED] | |||
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP) | |||
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{{Product_structure_help}} | {{Product_structure_help}} | ||
<!--Structure_notes--></protect> | </td><td></protect> | ||
==== Structure figures ==== | |||
{{File:1ZPQ.pdb}} | |||
{{File:1ZS4.pdb}} | |||
<protect><!-- ***** PLEASE DO NOT EDIT BELOW THIS LINE ***** --> | |||
</td><tr><table><!--Structure_notes--></protect> | |||
===Notes=== | ===Notes=== | ||
See ''Crystal structure of bacteriophage lambda cII and its DNA complex''<ref name='PMID:16039594'/> , [http://www.rcsb.org/pdb/explore/explore.do?structureId=1ZPQ| PDB 1ZPQ (protein alone)], or [http://www.rcsb.org/pdb/explore/explore.do?structureId=1ZS4| PDB 1ZS4 (protein/DNA complex)]. | |||
==Gene Product Resources== | ==Gene Product Resources== | ||
{{BacktoTop}} | |||
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===Notes=== | ===Notes=== | ||
==Accessions in Other Databases== | ==Accessions in Other Databases== | ||
{{BacktoTop}} | |||
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!Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
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==Links== | ==Links== | ||
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<noinclude> | <noinclude> | ||
==References== | ==References== | ||
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{{RefHelp}} | {{RefHelp}} | ||
<references/> | <references /> | ||
__NOTOC__ | __NOTOC__ | ||
===Categories=== | |||
{{BacktoTop}} | |||
[[Category:FtsH substrates]] | |||
Latest revision as of 20:19, 17 February 2015
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
cII |
|---|---|
| Synonyms |
cII, lambdap59 |
| Product description |
activator of Pre and Pi |
| EC number (for enzymes) |
|
| edit table |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0019044 |
maintenance of viral latency |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0019043 |
establishment of viral latency |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| edit table |
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Interactions
<protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MVRANKRNEA LRIESALLNK IAMLGTEKTA EAVGVDKSQI SRWKRDWIPK FSMLLAVLEW GVVDDDMARL ARQVAAILTN KKRPAATERS EQIQMEF |
| Length |
97 |
| Mol. Wt |
11.055 kDa |
| pI |
10.1 (calculated) |
| Extinction coefficient |
16,500 (calc based on 0 Y, 3 W, and 0 C residues) |
| edit table |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki. |
Structure figures
| See Help:Jmol in EcoliWiki Biological assembly of cII protein, PDB:1ZPQ |
| See Help:Jmol in EcoliWiki cII Protein/DNA complex: biological function. PDB:1ZS4l |
Notes
See Crystal structure of bacteriophage lambda cII and its DNA complex[4] , PDB 1ZPQ (protein alone), or PDB 1ZS4 (protein/DNA complex).
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
| edit table |
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Notes
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- ↑ Obuchowski, M et al. (1997) Stability of CII is a key element in the cold stress response of bacteriophage lambda infection. J. Bacteriol. 179 5987-91 PubMed
- ↑ Kobiler, O et al. (2002) The phage lambda CII transcriptional activator carries a C-terminal domain signaling for rapid proteolysis. Proc. Natl. Acad. Sci. U.S.A. 99 14964-9 PubMed
- ↑ Ho, YS & Rosenberg, M (1985) Characterization of a third, cII-dependent, coordinately activated promoter on phage lambda involved in lysogenic development. J. Biol. Chem. 260 11838-44 PubMed
- ↑ Jain, D et al. (2005) Crystal structure of bacteriophage lambda cII and its DNA complex. Mol. Cell 19 259-69 PubMed
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