msbA:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
||
||
MsbA  
MsbA
|-
|-
!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK0905, JW0897, b0914''
|-
|-
!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
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****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
{|   id="B46aa4b479d593"  class=" tableEdit GO_table_product dataTable"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="B46aa4b479d593"  class=" tableEdit GO_table_product dataTable"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
|
GO:0005319
GO:0005515
|
|
lipid transporter activity
protein binding
|
|
GOA:hamap<br />GO_REF:0000020
PMID:18344567
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
HAMAP:MF_01703
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001140
|
|
F
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|
|


|
|
GO:0005524
complete
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003439
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-  
|-  
|
|


|
|
GO:0005524
GO:0034040
|
|
ATP binding
lipid-transporting ATPase activity
|
|
GOA:interpro<br />GO_REF:0000002
PMID:18344567
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
InterPro:IPR011527
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
|
F
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|
|


|
|
GO:0005524
complete
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR017871
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|
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integral to membrane
integral to membrane
|
|
GOA:interpro<br />GO_REF:0000002
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR011527
SP_KW:KW-0812
|
|
C
C
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-
|
 
|
GO:0008289
|
lipid binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|
 
|
F
|
 
|
complete
|-  
|-  
|
|
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|


|
|
GO:0005515
GO:0016021
|
|
protein binding
integral to membrane
|
|
PMID:18344567
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IDA: Inferred from Direct Assay
IEA: Inferred from Electronic Annotation
|
|
 
SP_KW:KW-0812
|
|
C
C
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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integral to membrane
integral to membrane
|
|
GOA:spkw<br />SP_KW:GO_REF:0000004
GO_REF:0000023
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0812
SP_SL:SL-9909
|
|
C
C
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Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|


|
|
GO:0034040
GO:0055085
|
|
lipid-transporting ATPase activity
transmembrane transport
|
|
PMID:18344567
GOA:interpro<br />GO_REF:0000002
|
|
IDA: Inferred from Direct Assay
IEA: Inferred from Electronic Annotation
|
|
 
InterPro:IPR001140
|
|
F
P
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0016021
GO:0055085
|
|
integral to membrane
transmembrane transport
|
|
GO_REF:0000023
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_SL:SL-9909
InterPro:IPR011527
|
|
C
P
|
|
Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|


|
|
GO:0008289
GO:0005319
|
|
lipid binding
lipid transporter activity
|
|
PMID:18344567
GOA:hamap<br />GO_REF:0000020
|
|
IDA: Inferred from Direct Assay
IEA: Inferred from Electronic Annotation
|
|
 
HAMAP:MF_01703
|
|
F
F
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0055085
GO:0005524
|
|
transmembrane transport
ATP binding
|
|
GOA:interpro<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
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InterPro:IPR001140
InterPro:IPR001140
|
|
P
F
|
|
Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete
|-  
|-  
|
|


|
|
GO:0008144
GO:0005524
|
|
drug binding
ATP binding
|
|
PMID:18344567
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003439
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|
IDA: Inferred from Direct Assay
complete
|-
|
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011527
|
|
F
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0055085
GO:0005524
|
|
transmembrane transport
ATP binding
|
|
GOA:interpro<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR011527
InterPro:IPR017871
|
|
P
F
|
|
Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|
complete


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{|   id="S46aa4b481bdb2"  class=" tableEdit Product_interactions_table dataTable"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aa4b481bdb2"  class=" tableEdit Product_interactions_table dataTable"   
|- {{table heading style}}
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|   id="G46a7dd1c2b935"  class=" tableEdit Product_localization_table"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="G46a7dd1c2b935"  class=" tableEdit Product_localization_table"   
|- {{table heading style}}
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-  
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{|  id="W46aa4b49d4e91"  class=" tableEdit Product_phys_prop_table"   
{|  id="W46aa4b49d4e91"  class=" tableEdit Product_phys_prop_table"   
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!align=left {{table heading style}} |Name
||


|-
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LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>  
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>
|-
|-
!align=left {{table heading style}} |Length
!align=left {{table heading style}} |Length
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M46aa4b4a3c914"  class=" tableEdit Product_motif_table dataTable"   
|- {{table heading style}}
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!|Type!!Residues!!Description!!Notes!!References
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
24..298
|
[http://pfam.janelia.org/family/PF00664 PF00664  ABC transporter transmembrane region]
|
|
PMID:19920124
|-
|
Domain
|
383..509
|
[http://pfam.janelia.org/family/PF00005 PF00005  ABC transporter]
|
|
PMID:19920124


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View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P60752 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P60752 PSI-PRED (P60752)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P60752 Genomes TO Protein (P60752)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference
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{|   id="C46aa4b4b2e146"  class=" tableEdit Gene_accessions_table"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="C46aa4b4b2e146"  class=" tableEdit Gene_accessions_table"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10613-MONOMER EcoCyc:EG10613-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein/16128881 GI:16128881]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415434.1 GeneID:945530]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0003113
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P60752 UniProtKB/Swiss-Prot:P60752]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10613
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10613
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[[uniprot:P60752|UniProt:P60752]]
[http://www.ncbi.nlm.nih.gov/gene?term=945530 GeneID:945530]
|
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664]
RegulonDB:ECK120000606
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
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|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434]
EchoBASE:EB0608
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:RefGenome_Annotated_Gene]]
[[Category:Pfam:PF00664_!_ABC transporter transmembrane region]]
[[Category:Pfam:PF00005_!_ABC transporter]]
[[Category:RefGenome_Annotated_Gene]]
[[Category:RefGenome_Annotated_Gene]]

Latest revision as of 20:54, 6 July 2021

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MsbA

Synonyms

fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1], ECK0905, JW0897, b0914

Product description

ATP-binding transport protein[2][3]

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4]

EC number (for enzymes)



Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0034040

lipid-transporting ATPase activity

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

P

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

P

Seeded from EcoCyc (v14.0)

complete

GO:0006869

lipid transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0445

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

PMID:16858726[6]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0008289

lipid binding

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

P

Seeded from EcoCyc (v14.0)

complete

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

P

Seeded from EcoCyc (v14.0)

complete

GO:0005319

lipid transporter activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 6 predicted transmembrane domains

Daley et al. (2005) [7]



Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ
Length

582

Mol. Wt

64.462 kDa

pI

8.8 (calculated)

Extinction coefficient

46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

24..298

PF00664 ABC transporter transmembrane region

PMID:19920124[8]

Domain

383..509

PF00005 ABC transporter

PMID:19920124[8]

<motif_map/>

tmhmm.php?gene=msbA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=msbA taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128881

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945530

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003113

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P60752

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10613

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10613

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945530

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000606

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0608

Escherichia coli str. K-12 substr. MG1655


Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Eckford, PD & Sharom, FJ (2008) Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates. J. Biol. Chem. 283 12840-50 PubMed
  6. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  7. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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