mdh:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''mdh''  
''mdh''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3225, b3236, JW3205''<ref name='LIB:Riley_2006'/>
''ECK3225, b3236, JW3205''<ref name='LIB:Riley_2006'/>, JW3205''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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malate dehydrogenase, NAD(P)-binding<ref name='LIB:Riley_2006'/>, B3236<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''malate dehydrogenase, NAD(P)-binding<ref name='LIB:Riley_2006'/>, B3236<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3225, JW3205, b3236''
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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
<GO_nr />
* GO:0005739 mitochondrion ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005624 membrane fraction ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005829 cytosol ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0000300 peripheral to membrane of membrane fraction ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0016615 malate dehydrogenase activity ([http://www.geneontology.org/GO.evidence.shtml IMP,IDA])
* GO:0016491 oxidoreductase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0006108 malate metabolic process ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0009061 anaerobic respiration ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0006113 fermentation ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0006099 tricarboxylic acid cycle ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0006096 glycolysis ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Quick Links
!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=mdh&loc=MG1655:3382290..3381352,W3110:3384123..3383185,REL606:3312165..3311227,DH10B:3480035..3479097 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3480035&end=3479097&gene=mdh&aa=mkvavlgaaggigqalalllktqlpsgselslydiapvtpgvavdlshiptavkikgfsgedatpalegadvvlisagvarkpgmdrsdlfnvnagivknlvqqvaktcpkacigiitnpvnttvaiaaevlkkagvydknklfgvttldiirsntfvaelkgkqpgevevpvigghsgvtilpllsqvpgvsfteqevadltkriqnagtevveakagggsatlsmgqaaarfglslvralqgeqgvvecayvegdgqyarffsqplllgkngveerksigtlsafeqnalegmldtlkkdialgeefvnk Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mdh+AND+escherichia+coli Pubmed(mdh)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=mdh Textpresso(mdh)]
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mdh&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10576]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000569&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mdh&loc=MG1655%3A3382290..3381352,W3110%3A3384123..3383185,REL606%3A3312165..3311227,DH10B%3A3480035..3479097,BW2952%3A3268500..3269438]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3268500&end=3269438&gene=mdh&aa=mkvavlgaaggigqalalllktqlpsgselslydiapvtpgvavdlshiptavkikgfsgedatpalegadvvlisagvarkpgmdrsdlfnvnagivknlvqqvaktcpkacigiitnpvnttvaiaaevlkkagvydknklfgvttldiirsntfvaelkgkqpgevevpvigghsgvtilpllsqvpgvsfteqevadltkriqnagtevveakagggsatlsmgqaaarfglslvralqgeqgvvecayvegdgqyarffsqplllgkngveerksigtlsafeqnalegmldtlkkdialgeefvnk]]&nbsp;&nbsp; [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mdh+AND+escherichia+coli]]&nbsp;&nbsp; [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mdh]]&nbsp;&nbsp;


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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

mdh

Gene Synonym(s)

ECK3225, b3236, JW3205[1], JW3205

Product Desc.

Mdh[2][3];

Component of malate dehydrogenase[2][3]

Malate dehydrogenase, NAD-dependent[4]

Product Synonyms(s)

malate dehydrogenase, NAD(P)-binding[1], B3236[2][1], Mdh[2][1] , ECK3225, JW3205, b3236

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mdh[2], OP00149

Regulation/Activity
Quick Links



        

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Notes

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Mdh is elevated 4X during growth at 4C (enabled by Oleispira antarctica Cpn10/60 transgene). Deletion of mdh induces growth defects on all substrates except glucose. After four hours of Zn(II) stress, protein levels increased (Easton, 2006).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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