msbA:Gene Product(s): Difference between revisions

Standard name	MsbA
Synonyms	fused lipid transporter subunits of ABC superfamily: membrane component^[1], ATP-binding component^[1], B0914^[2]^[1], MsbA^[2]^[1], ECK0905, JW0897, b0914
Product description	ATP-binding transport protein^[2]^[3] Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005515	protein binding	PMID:18344567^[5]	IDA: Inferred from Direct Assay		F		complete
	GO:0034040	lipid-transporting ATPase activity	PMID:18344567^[5]	IDA: Inferred from Direct Assay		F		complete
	GO:0005524	ATP binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C	Seeded from EcoCyc (v14.0)	complete
	GO:0006869	lipid transport	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01703	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006869	lipid transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011917	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006869	lipid transport	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0445	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	PMID:16858726^[6]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001140	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0008289	lipid binding	PMID:18344567^[5]	IDA: Inferred from Direct Assay		F		complete
	GO:0016021	integral to membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011917	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-9909	C	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001140	P	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011527	P	Seeded from EcoCyc (v14.0)	complete
	GO:0005319	lipid transporter activity	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01703	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001140	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003439	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011527	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011917	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017871	F	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
plasma membrane	C-terminus localized in the cytoplasm with 6 predicted transmembrane domains	Daley et al. (2005) ^[7]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ
Length	582
Mol. Wt	64.462 kDa
pI	8.8 (calculated)
Extinction coefficient	46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	24..298	PF00664 ABC transporter transmembrane region	PMID:19920124^[8]
Domain	383..509	PF00005 ABC transporter	PMID:19920124^[8]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=msbA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16128881	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:945530	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0003113	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P60752	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG10613	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG10613	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:945530	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120000606	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB0608	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 Eckford, PD & Sharom, FJ (2008) Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates. J. Biol. Chem. 283 12840-50 PubMed
↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ ^8.0 ^8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

msbA:Gene Product(s): Difference between revisions

Latest revision as of 20:54, 6 July 2021

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 35: / Line 35: @@
 *
 ****************************************************************************************** -->{{Product_nomenclature_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="S46aa4b46a0d97"  class=" tableEdit Product_nomenclature_table"
 |-
 !align=left {{table heading style}} |Standard name
 ||
 MsbA
 |-
 !align=left {{table heading style}} |Synonyms
 ||
-fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK0905, JW0897, b0914''
 |-
 !align=left {{table heading style}} |Product description
@@ Line 56: / Line 56: @@
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+|- class="tableEdit_footer"
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+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b46a0d97&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b46a0d97-->
@@ Line 72: / Line 72: @@
 ******************************************************************************************
 *
-*   ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
+** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
 *
 ****************************************************************************************** -->{{Product_GO_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="B46aa4b479d593"  class=" tableEdit GO_table_product dataTable"
 |- {{table_heading_style}}
-!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
 |-
 |
 |
-GO:0005319
+GO:0005515
-|
-lipid transporter activity
-|
-PMID:11278265
 |
-IMP: Inferred from Mutant Phenotype
+protein binding
 |
+PMID:18344567
-|
-F
-|
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
-|
-complete
-|-
-|
-|
-GO:0005524
-|
-ATP binding
-|
-PMID:8809774
 |
 IDA: Inferred from Direct Assay
@@ Line 112: / Line 93: @@
 |
 F
-|
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
-|
-complete
-|-
-|
-|
-GO:0005624
-|
-membrane fraction
-|
-PMID:16858726
-|
-IDA: Inferred from Direct Assay
 |
-|
-C
-|
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 139: / Line 101: @@
 |
-GO:0006869
+GO:0034040
-|
-lipid transport
 |
-PMID:11278265
+lipid-transporting ATPase activity
 |
-IMP: Inferred from Mutant Phenotype
+PMID:18344567
-|
-|
-P
-|
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
-|
-complete
-|-
-|
-|
-GO:0015437
-|
-lipopolysaccharide-transporting ATPase activity
-|
-PMID:12119303
 |
 IDA: Inferred from Direct Assay
@@ Line 170: / Line 113: @@
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 177: / Line 120: @@
 |
-GO:0016887
+GO:0005524
 |
-ATPase activity
+ATP binding
 |
-PMID:12119303
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0067
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 196: / Line 139: @@
 |
-GO:0000166
+GO:0005886
 |
-nucleotide binding
+plasma membrane
 |
-GO_REF:0000002<br />GO_REF:0000004
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593<br />SP_KW:KW-0547
+SP_KW:KW-0997
 |
-F
+C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 215: / Line 158: @@
 |
-GO:0005319
+GO:0005886
 |
-lipid transporter activity
+plasma membrane
 |
-GO_REF:0000020
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-HAMAP:MF_01703
+SP_KW:KW-1003
 |
-F
+C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 234: / Line 177: @@
 |
-GO:0005524
+GO:0006869
 |
-ATP binding
+lipid transport
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:hamap<br />GO_REF:0000020
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR003439<br />InterPro:IPR011527<br />InterPro:IPR011917<br />SP_KW:KW-0067
+HAMAP:MF_01703
 |
-F
+P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 253: / Line 196: @@
 |
-GO:0006810
+GO:0006869
 |
-transport
+lipid transport
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR011527<br />SP_KW:KW-0813
+InterPro:IPR011917
 |
 P
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 276: / Line 219: @@
 lipid transport
 |
-GO_REF:0000002<br />GO_REF:0000004<br />GO_REF:0000020
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR011917<br />SP_KW:KW-0445<br />HAMAP:MF_01703
+SP_KW:KW-0445
 |
 P
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 291: / Line 234: @@
 |
-GO:0009276
+GO:0016020
 |
-Gram-negative-bacterium-type cell wall
+membrane
 |
-GO_REF:0000002
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR011917
+SP_KW:KW-0472
 |
 C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 314: / Line 257: @@
 membrane
 |
-GO_REF:0000004<br />GO_REF:0000004
+PMID:16858726
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-SP_KW:KW-0397<br />SP_KW:KW-0472
 |
 C
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 333: / Line 276: @@
 integral to membrane
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR011527<br />InterPro:IPR011917<br />SP_KW:KW-0812
+InterPro:IPR001140
 |
 C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 348: / Line 291: @@
 |
-GO:0016787
+GO:0016021
 |
-hydrolase activity
+integral to membrane
 |
-GO_REF:0000004
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0378
+SP_KW:KW-0812
 |
-F
+C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 367: / Line 310: @@
 |
-GO:0016887
+GO:0008289
 |
-ATPase activity
+lipid binding
 |
-GO_REF:0000002
+PMID:18344567
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
-|
-InterPro:IPR003439
-|
-F
-|
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
-|
-complete
-|-
-|
-|
-GO:0017111
-|
-nucleoside-triphosphatase activity
-|
-GO_REF:0000002
-|
-IEA: Inferred from Electronic Annotation
-|
-InterPro:IPR003593
-|
-F
-|
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
-|
-complete
-|-
 |
-|
-GO:0042626
-|
-ATPase activity, coupled to transmembrane movement of substances
-|
-GO_REF:0000002<br />GO_REF:0000002
-|
-IEA: Inferred from Electronic Annotation
-|
-InterPro:IPR001140<br />InterPro:IPR011527
 |
 F
-|
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
-|
-complete
-|-
-|
-|
-GO:0005739
-|
-mitochondrion
-|
-PMID:16858726
-|
-IDA: Inferred from Direct Assay
 |
-|
-C
-|
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 443: / Line 329: @@
 |
-GO:0005886
+GO:0016021
 |
-plasma membrane
+integral to membrane
 |
-GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
+InterPro:IPR011917
 |
 C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 462: / Line 348: @@
 |
-GO:0000166
+GO:0016021
 |
-nucleotide binding
+integral to membrane
 |
-GO_REF:0000002<br />GO_REF:0000004
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593<br />SP_KW:KW-0547
+SP_KW:KW-0812
-|
-F
-|
-Seeded from EcoCyc
-|
-complete
-|-
-|
-|
-GO:0005319
-|
-lipid transporter activity
-|
-GO_REF:0000020<br />PMID:11278265
-|
-IMP: Inferred from Mutant Phenotype
-|
-HAMAP:MF_01703<br />
-|
-F
-|
-Seeded from EcoCyc
-|
-complete
-|-
-|
-|
-GO:0005524
-|
-ATP binding
-|
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004<br />PMID:8809774
-|
-IDA: Inferred from Direct Assay
-|
-InterPro:IPR001140<br />InterPro:IPR003439<br />InterPro:IPR011527<br />InterPro:IPR011917<br />InterPro:IPR017871<br />SP_KW:KW-0067<br />
-|
-F
-|
-Seeded from EcoCyc
-|
-complete
-|-
-|
-|
-GO:0005624
-|
-membrane fraction
-|
-PMID:16858726
-|
-IDA: Inferred from Direct Assay
-|
 |
 C
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 538: / Line 367: @@
 |
-GO:0005886
+GO:0016021
 |
-plasma membrane
+integral to membrane
 |
-GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
+GO_REF:0000023
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
+SP_SL:SL-9909
 |
 C
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 557: / Line 386: @@
 |
-GO:0006810
+GO:0055085
 |
-transport
+transmembrane transport
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR011527<br />SP_KW:KW-0813
+InterPro:IPR001140
 |
 P
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 576: / Line 405: @@
 |
-GO:0006869
+GO:0055085
 |
-lipid transport
+transmembrane transport
 |
-GO_REF:0000020<br />GO_REF:0000002<br />GO_REF:0000004<br />PMID:11278265
+GOA:interpro<br />GO_REF:0000002
 |
-IMP: Inferred from Mutant Phenotype
+IEA: Inferred from Electronic Annotation
 |
-HAMAP:MF_01703<br />InterPro:IPR011917<br />SP_KW:KW-0445<br />
+InterPro:IPR011527
 |
 P
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 595: / Line 424: @@
 |
-GO:0009276
+GO:0005319
 |
-Gram-negative-bacterium-type cell wall
+lipid transporter activity
 |
-GO_REF:0000002
+GOA:hamap<br />GO_REF:0000020
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR011917
+HAMAP:MF_01703
-|
-C
-|
-Seeded from EcoCyc
-|
-complete
-|-
-|
-|
-GO:0015437
-|
-lipopolysaccharide-transporting ATPase activity
-|
-PMID:12119303
-|
-IDA: Inferred from Direct Assay
-|
 |
 F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 633: / Line 443: @@
 |
-GO:0016020
+GO:0005524
 |
-membrane
+ATP binding
 |
-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0472
+InterPro:IPR001140
 |
-C
+F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 652: / Line 462: @@
 |
-GO:0016021
+GO:0005524
 |
-integral to membrane
+ATP binding
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR011527<br />InterPro:IPR011917<br />SP_KW:KW-0812
+InterPro:IPR003439
 |
-C
+F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 671: / Line 481: @@
 |
-GO:0016787
+GO:0005524
 |
-hydrolase activity
+ATP binding
 |
-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0378
+InterPro:IPR011527
 |
 F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 690: / Line 500: @@
 |
-GO:0016887
+GO:0005524
 |
-ATPase activity
+ATP binding
-|
-GO_REF:0000002<br />GO_REF:0000002<br />PMID:12119303
-|
-IDA: Inferred from Direct Assay
-|
-InterPro:IPR003439<br />InterPro:IPR017871<br />
-|
-F
-|
-Seeded from EcoCyc
-|
-complete
-|-
-|
-|
-GO:0017111
 |
-nucleoside-triphosphatase activity
+GOA:interpro<br />GO_REF:0000002
-|
-GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593
+InterPro:IPR011917
 |
 F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 728: / Line 519: @@
 |
-GO:0042626
+GO:0005524
 |
-ATPase activity, coupled to transmembrane movement of substances
+ATP binding
 |
-GO_REF:0000002<br />GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001140<br />InterPro:IPR011527
+InterPro:IPR017871
 |
 F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
+|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593-->
@@ Line 757: / Line 548: @@
 *
 ****************************************************************************************** -->{{Product_interactions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aa4b481bdb2"  class=" tableEdit Product_interactions_table dataTable"
 |- {{table heading style}}
 !|Partner Type!!Partner!!Notes!!References!!Evidence
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2-->
@@ Line 778: / Line 569: @@
 *
 ****************************************************************************************** -->{{Product_localization_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="G46a7dd1c2b935"  class=" tableEdit Product_localization_table"
 |- {{table heading style}}
-!|Compartment!!Description!!Evidence!!Notes
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
 |-
 |
@@ Line 788: / Line 579: @@
 |
 Daley et al. (2005) <ref name=PMID:15919996/>
+|
 |
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935-->
@@ Line 812: / Line 605: @@
 *
 ****************************************************************************************** -->{{Product_physical_properties_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="W46aa4b49d4e91"  class=" tableEdit Product_phys_prop_table"
+|-
+!align=left {{table heading style}} |Name
+||
 |-
@@ Line 827: / Line 624: @@
 LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
 LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
 TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>
 |-
 !align=left {{table heading style}} |Length
@@ Line 845: / Line 642: @@
 ,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91-->
@@ Line 863: / Line 660: @@
 *
 ****************************************************************************************** -->{{Product_domains_motifs_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M46aa4b4a3c914"  class=" tableEdit Product_motif_table dataTable"
 |- {{table heading style}}
-!|Type!!Residues!!Description!!Notes
+!|Type!!Residues!!Description!!Notes!!References
+|-
+|
+Domain
+|
+..298
+|
+[http://pfam.janelia.org/family/PF00664 PF00664  ABC transporter transmembrane region]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..509
+|
+[http://pfam.janelia.org/family/PF00005 PF00005  ABC transporter]
+|
-|-class='sortbottom'
+|
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || ||
+PMID:19920124
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914-->
@@ Line 891: / Line 710: @@
 *
 ****************************************************************************************** -->{{Product_structure_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="A46a7dd1dc9beb"  class=" tableEdit Product_structure_table"
 |-
@@ Line 904: / Line 723: @@
 ||
 View models at:
-* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
+* [http://www.proteinmodelportal.org/query/uniprot/P60752 Protein Model Portal]
-* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P60752 PSI-PRED (P60752)]
-* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P60752 Genomes TO Protein (P60752)] (GTOP)
-* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
-* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb-->
@@ Line 949: / Line 766: @@
 *
 ****************************************************************************************** -->{{Product_resources_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Q46aa4b4ad5f6c"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
 !|Resource type!!Source!!Notes/Reference
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c-->
@@ Line 971: / Line 788: @@
 *
 ****************************************************************************************** -->{{Gene_accessions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="C46aa4b4b2e146"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
 !|Database!!Accession!!Notes
 |-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/16128881 GI:16128881]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/NP_415434.1 GeneID:945530]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[ASAP]]
+|
+ASAP:ABE-0003113
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
+|-
+|
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+|
+[http://www.uniprot.org/uniprot/P60752 UniProtKB/Swiss-Prot:P60752]
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10613-MONOMER EcoCyc:EG10613-MONOMER]
+Escherichia coli str. K-12 substr. MG1655
+|-
 |
+[[EcoCyc]]
+|
+EcoCyc:EG10613
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[[EcoGene]]
 |
-[[uniprot:P60752|UniProt:P60752]]
+EcoGene:EG10613
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664]
+[http://www.ncbi.nlm.nih.gov/gene?term=945530 GeneID:945530]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434]
+RegulonDB:ECK120000606
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://salilab.org/modbase/searchbyid?databaseID=P60752 ModBase:P60752]
+EchoBASE:EB0608
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.C46aa4b4b2e146&page=21674&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.C46aa4b4b2e146&page=21674&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.C46aa4b4b2e146-->
@@ Line 1,028: / Line 873: @@
 *
 ****************************************************************************************** -->
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="I46a7dd2144523"  class=" tableEdit Links_table"
 |- {{table_heading_style}}
 !|Name!!URL!!Comments
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.I46a7dd2144523&page=21674&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.I46a7dd2144523&page=21674&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.21674.I46a7dd2144523-->
@@ Line 1,049: / Line 894: @@
 {{BacktoTop}}
 [[Category:Proteins]]
+[[Category:RefGenome_Annotated_Gene]]
+[[Category:Pfam:PF00664_!_ABC transporter transmembrane region]]
+[[Category:Pfam:PF00005_!_ABC transporter]]
+[[Category:RefGenome_Annotated_Gene]]

msbA:Gene Product(s): Difference between revisions

Latest revision as of 20:54, 6 July 2021

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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