alsE:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
||
||
AlsE product
AlsE  
|-
|-
!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
allulose-6-phosphate 3-epimerase product<ref name='LIB:Riley_2006'/>, B4085 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjcU product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AlsE product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''allulose-6-phosphate 3-epimerase<ref name='LIB:Riley_2006'/>, B4085<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjcU<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AlsE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4078, JW4046, yjcU, b4085''
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
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ribulose-phosphate 3-epimerase activity
ribulose-phosphate 3-epimerase activity
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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F
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0005975
|
carbohydrate metabolic process
|
GO_REF:0000002<br />GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000056<br />SP_KW:KW-0119
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0003824
|
catalytic activity
|
GO_REF:0000002<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011060<br />InterPro:IPR013785
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0008152
|
metabolic process
|
GO_REF:0000002<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011060<br />InterPro:IPR013785
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0016853
|
isomerase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0413
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:P35340
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0016857
|
racemase and epimerase activity, acting on carbohydrates and derivatives
|
PMID:18700786
|
IDA: Inferred from Direct Assay
|
 
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|
 
|
GO:0019316
|
D-allose catabolic process
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PMID:10559180
|
IMP: Inferred from Mutant Phenotype
|
 
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
 
|
GO:0034700
|
allulose 6-phosphate 3-epimerase activity
|
PMID:18700786
|
IDA: Inferred from Direct Assay
|
 
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
|
complete  
complete  
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complete  
complete  


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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1147423<br />  
Experiment(s):EBI-1147423<br />  


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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes


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!align=left {{table heading style}} |Name
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AMKYYIHKAD KITVMTVDPG FAGQPFIPEM LDKLAELKAW REREGLEYEI EVDGSCNQAT
AMKYYIHKAD KITVMTVDPG FAGQPFIPEM LDKLAELKAW REREGLEYEI EVDGSCNQAT
YEKLMAAGAD VFIVGTSGLF NHAENIDEAW RIMTAQILAA KSEVQPHAKT A</pre>  
YEKLMAAGAD VFIVGTSGLF NHAENIDEAW RIMTAQILAA KSEVQPHAKT A</pre>  
|-
!align=left {{table heading style}} |Length
||
231
|-
|-
!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
26.11 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
26.109 kDa
|-
|-
!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
5.4 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
||
||
19940 - 20315 (calc based on 6 Y, 2 W, and 3 C residues)  
19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)


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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
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|- {{table heading style}}
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
2..203
|
[http://pfam.janelia.org/family/PF00834 PF00834  Ribulose-phosphate 3 epimerase family]
|


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PMID:19920124
 
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<td>
<!-- motifs column 2-->
<motif_map/>
</td>
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</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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|-
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!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>alsE
<beststructure>
562</beststructure>
gene=alsE
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=alsE&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P32719 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=alsE&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P32719 PSI-PRED (P32719)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P32719 Genomes TO Protein (P32719)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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|- {{table_heading_style}}
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11957-MONOMER EcoCyc:EG11957-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein/16131911 GI:16131911]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418509.1 GeneID:948595]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0013382
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P32719 UniProtKB/Swiss-Prot:P32719]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11957
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoGene]]
|
|
[[uniprot:P32719|UniProt:P32719]]
EcoGene:EG11957
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00834 PFAM:PF00834]
[http://www.ncbi.nlm.nih.gov/gene?term=948595 GeneID:948595]
|
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418509 RefSeq:NP_418509]
RegulonDB:ECK120001884
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P32719 ModBase:P32719]
EchoBASE:EB1900
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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==References==
==References==
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===Categories===
===Categories===
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[[Category:Proteins]]
[[Category:Proteins]]
[[Category:Pfam:PF00834_!_Ribulose-phosphate 3 epimerase family]]

Latest revision as of 21:12, 17 February 2015

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AlsE

Synonyms

allulose-6-phosphate 3-epimerase[1], B4085[2][1], YjcU[2][1], AlsE[2][1] , ECK4078, JW4046, yjcU, b4085

Product description

EG11957[2][3]

Allulose-6-P 3-epimerase[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004750

ribulose-phosphate 3-epimerase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000056

F

Seeded from EcoCyc (v14.0)

complete

GO:0019316

D-allose catabolic process

PMID:10559180[5]

IMP: Inferred from Mutant Phenotype

P

alsE insertion mutants can't grow on D-allose as the sole carbon source.

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ahpF

PMID:16606699[6]

Experiment(s):EBI-1147423
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MKISPSLMCM DLLKFKEQIE FIDSHADYFH IDIMDGHFVP NLTLSPFFVS QVKKLATKPL
DCHLMVTRPQ DYIAQLARAG ADFITLHPET INGQAFRLID EIRRHDMKVG LILNPETPVE
AMKYYIHKAD KITVMTVDPG FAGQPFIPEM LDKLAELKAW REREGLEYEI EVDGSCNQAT
YEKLMAAGAD VFIVGTSGLF NHAENIDEAW RIMTAQILAA KSEVQPHAKT A
Length

231

Mol. Wt

26.109 kDa

pI

5.4 (calculated)

Extinction coefficient

19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

2..203

PF00834 Ribulose-phosphate 3 epimerase family

PMID:19920124[7]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=alsE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131911

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948595

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013382

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P32719

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11957

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11957

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948595

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001884

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1900

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Poulsen, TS et al. (1999) D-Allose catabolism of Escherichia coli: involvement of alsI and regulation of als regulon expression by allose and ribose. J. Bacteriol. 181 7126-30 PubMed
  6. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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