htpG:Gene Product(s): Difference between revisions
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****************************************************************************************** -->{{Product_nomenclature_help}} | ****************************************************************************************** -->{{Product_nomenclature_help}} | ||
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!align=left {{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
|| | || | ||
molecular chaperone HSP90 family<ref name='LIB:Riley_2006'/>, B0473<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, C62.5<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsp90<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''molecular chaperone HSP90 family<ref name='LIB:Riley_2006'/>, B0473<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, C62.5<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsp90<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0467, JW0462, b0473'' | ||
|- | |- | ||
!align=left {{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
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****************************************************************************************** -->{{Product_GO_help}} | ****************************************************************************************** -->{{Product_GO_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa321f28bf5" class=" tableEdit GO_table_product dataTable" | ||
|- {{table_heading_style}} | |- {{table_heading_style}} | ||
!|Qualifier!!GO ID!!GO term name!!Reference | !|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
|- | |- | ||
| | | | ||
| | | | ||
GO: | GO:0000166 | ||
| | | | ||
nucleotide binding | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
SP_KW:KW-0547 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 103: | Line 103: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:hamap<br />GO_REF:0000020 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
HAMAP:MF_00505 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 122: | Line 122: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR001404 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 141: | Line 141: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR003594 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 160: | Line 160: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR019805 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 179: | Line 179: | ||
| | | | ||
GO: | GO:0005524 | ||
| | | | ||
ATP binding | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
SP_KW:KW-0067 | |||
| | | | ||
F | F | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 198: | Line 198: | ||
| | | | ||
GO: | GO:0005829 | ||
| | | | ||
cytosol | |||
| | | | ||
PMID:16858726 | |||
| | | | ||
IDA: Inferred from Direct Assay | |||
| | | | ||
| | | | ||
C | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 217: | Line 217: | ||
| | | | ||
GO: | GO:0005886 | ||
| | | | ||
plasma membrane | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0997 | |||
| | | | ||
C | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 236: | Line 236: | ||
| | | | ||
GO: | GO:0005886 | ||
| | | | ||
plasma membrane | |||
| | | | ||
GO_REF:0000004 | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW- | SP_KW:KW-1003 | ||
| | | | ||
C | C | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 259: | Line 259: | ||
protein folding | protein folding | ||
| | | | ||
GOA:hamap<br />GO_REF:0000020 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
HAMAP:MF_00505 | |||
| | | | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 274: | Line 274: | ||
| | | | ||
GO: | GO:0006457 | ||
| | | | ||
protein folding | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR001404 | |||
| | | | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 293: | Line 293: | ||
| | | | ||
GO: | GO:0006457 | ||
| | | | ||
protein folding | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR019805 | |||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 312: | Line 312: | ||
| | | | ||
GO: | GO:0006950 | ||
| | | | ||
response to stress | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR001404 | InterPro:IPR001404 | ||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
|- | |- | ||
| | | | ||
| | | | ||
GO: | GO:0006950 | ||
| | | | ||
response to stress | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR019805 | |||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 388: | Line 350: | ||
| | | | ||
GO: | GO:0006950 | ||
| | | | ||
response to stress | |||
| | | | ||
GO_REF:0000004 | GOA:spkw<br />SP_KW:GO_REF:0000004 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW- | SP_KW:KW-0346 | ||
| | | | ||
P | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 407: | Line 369: | ||
| | | | ||
GO: | GO:0016020 | ||
| | | | ||
membrane | |||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_KW:KW-0472 | |||
| | | | ||
C | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 445: | Line 388: | ||
| | | | ||
GO: | GO:0019898 | ||
| | | | ||
extrinsic to membrane | |||
| | | | ||
GO_REF:0000023 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
SP_SL:SL-9903 | |||
| | | | ||
C | C | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 464: | Line 407: | ||
| | | | ||
GO: | GO:0009408 | ||
| | | | ||
response to heat | |||
| | | | ||
PMID: | PMID:8349564 | ||
| | | | ||
IEP: Inferred from Expression Pattern | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
| Line 483: | Line 426: | ||
| | | | ||
GO: | GO:0051082 | ||
| | | | ||
unfolded protein binding | |||
| | | | ||
GOA:hamap<br />GO_REF:0000020 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
HAMAP:MF_00505 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 502: | Line 445: | ||
| | | | ||
GO: | GO:0051082 | ||
| | | | ||
protein | unfolded protein binding | ||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
GO_REF: | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR001404 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 540: | Line 464: | ||
| | | | ||
GO: | GO:0051082 | ||
| | | | ||
unfolded protein binding | |||
| | | | ||
GO_REF: | GOA:interpro<br />GO_REF:0000002 | ||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR019805 | |||
| | | | ||
F | |||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
| Line 559: | Line 483: | ||
| | | | ||
GO: | GO:0006974 | ||
| | | | ||
response to DNA damage stimulus | |||
| | | | ||
PMID: | PMID:11967071 | ||
| | | | ||
IEP: Inferred from Expression Pattern | |||
| | | | ||
| | | | ||
P | |||
| | | | ||
| | | | ||
complete | complete | ||
|-class= | |- class="tableEdit_footer" | ||
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{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aa322796726" class=" tableEdit Product_interactions_table dataTable" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Partner Type!!Partner!!Notes!!References!!Evidence | !|Partner Type!!Partner!!Notes!!References!!Evidence | ||
| Line 794: | Line 680: | ||
| | | | ||
Experiment(s):EBI-1136800<br /> | Experiment(s):EBI-1136800<br /> | ||
|- | |||
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Protein | |||
| | |||
ugpB | |||
| | |||
|-class= | | | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.20615.A46aa322796726&page=20615&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || || | PMID:19402753 | ||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
hyfG | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
mcrB | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
yggR | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
ycbW | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- | |||
| | |||
Protein | |||
| | |||
yeaI | |||
| | |||
| | |||
PMID:19402753 | |||
| | |||
LCMS(ID Probability):99.0 | |||
|- class="tableEdit_footer" | |||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.20615.A46aa322796726&page=20615&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || || | |||
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****************************************************************************************** -->{{Product_localization_help}} | ****************************************************************************************** -->{{Product_localization_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="K46a7c398ef9f1" class=" tableEdit Product_localization_table" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Compartment!!Description!!Evidence!!Notes | !|Compartment!!Description!!Evidence!!Reference/Source!!Notes | ||
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****************************************************************************************** -->{{Product_physical_properties_help}} | ****************************************************************************************** -->{{Product_physical_properties_help}} | ||
{| | {| id="K46aa3229ae1c5" class=" tableEdit Product_phys_prop_table" | ||
|- | |||
!align=left {{table heading style}} |Name | |||
|| | |||
|- | |- | ||
| Line 861: | Line 817: | ||
!align=left {{table heading style}} |Mol. Wt | !align=left {{table heading style}} |Mol. Wt | ||
|| | || | ||
71. | 71.424 kDa | ||
|- | |- | ||
!align=left {{table heading style}} |pI | !align=left {{table heading style}} |pI | ||
|| | || | ||
5.0 (calculated) | |||
|- | |- | ||
!align=left {{table heading style}} |Extinction coefficient | !align=left {{table heading style}} |Extinction coefficient | ||
|| | || | ||
81,820 (calc based on 18 Y, 10 W, and 0 C residues) | |||
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|} | |} | ||
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****************************************************************************************** -->{{Product_domains_motifs_help}} | ****************************************************************************************** -->{{Product_domains_motifs_help}} | ||
{| | {| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="I46aa322a137ed" class=" tableEdit Product_motif_table dataTable" | ||
|- {{table heading style}} | |- {{table heading style}} | ||
!|Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes!!References | ||
|- | |||
| | |||
Modification Site | |||
| | |||
409 | |||
| | |||
phosphorylation site at S409 | |||
| | |||
[[PHOSIDA#p-values|probability less than 75%]] | |||
| | |||
PMID:17938405 | |||
|- | |||
| | |||
Modification Site | |||
| | |||
410 | |||
| | |||
phosphorylation site at S410 | |||
| | |||
[[PHOSIDA#p-values|probability less than 75%]] | |||
| | |||
PMID:17938405 | |||
|- | |||
| | |||
Modification Site | |||
| | |||
405 | |||
| | |||
phosphorylation site at T405 | |||
| | |||
[[PHOSIDA#p-values|probability less than 75%]] | |||
| | |||
PMID:17938405 | |||
|- | |||
| | |||
Modification Site | |||
| | |||
104 | |||
| | |||
phosphorylation site at S104 | |||
| | |||
[[PHOSIDA#p-values|probability greater than 75%]] | |||
| | |||
PMID:17938405 | |||
|- | |||
| | |||
Modification Site | |||
| | |||
404 | |||
| | |||
phosphorylation site at S404 | |||
| | |||
[[PHOSIDA#p-values|probability less than 75%]] | |||
| | |||
PMID:17938405 | |||
|- | |||
| | |||
Domain | |||
| | |||
27..183 | |||
| | |||
[http://pfam.janelia.org/family/PF02518 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase] | |||
| | |||
| | |||
PMID:19920124 | |||
|- | |||
| | |||
Domain | |||
| | |||
209..624 | |||
| | |||
[http://pfam.janelia.org/family/PF00183 PF00183 Hsp90 protein] | |||
| | |||
| | |||
PMID:19920124 | |||
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<span id='Structure'></span><big>'''Structure'''</big><br /> | |||
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!align=left {{table heading style}} |Structures | !align=left {{table heading style}} |Structures | ||
|| | || | ||
<beststructure>htpG | <beststructure> | ||
562</beststructure> | gene=htpG | ||
taxon=562,83333 | |||
</beststructure> | |||
|- | |- | ||
!align=left {{table heading style}} |Models | !align=left {{table heading style}} |Models | ||
|| | || | ||
View models at: | View models at: | ||
* [http:// | * [http://www.proteinmodelportal.org/query/uniprot/P0A6Z3 Protein Model Portal] | ||
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A6Z3 PSI-PRED (P0A6Z3)] | |||
* [http://bioinf.cs.ucl.ac.uk/ | * [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A6Z3 Genomes TO Protein (P0A6Z3)] (GTOP) | ||
* [http://spock.genes.nig.ac.jp/~genome/ | |||
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<!--Structure_notes--></protect> | </td><td></protect> | ||
==== Structure figures ==== | |||
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</td><tr><table><!--Structure_notes--></protect> | |||
===Notes=== | ===Notes=== | ||
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!|Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
|- | |- | ||
| | | | ||
[http:// | [http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | ||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/16128457 GI:16128457] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | |||
| | | | ||
[http:// | [http://www.ncbi.nlm.nih.gov/protein/NP_415006.1 GeneID:945099] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
| | |||
[[ASAP]] | |||
| | |||
ASAP:ABE-0001642 | |||
| | |||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |||
| | |||
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | |||
| | |||
[http://www.uniprot.org/uniprot/P0A6Z3 UniProtKB/Swiss-Prot:P0A6Z3] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[EcoCyc]] | |||
| | | | ||
EcoCyc:EG10461 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EcoGene]] | |||
| | | | ||
EcoGene:EG10461 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]]) | ||
| | | | ||
[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene?term=945099 GeneID:945099] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[RegulonDB]] | |||
| | | | ||
RegulonDB:ECK120000454 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EchoBASE]] | |||
| | | | ||
EchoBASE:EB0456 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
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==References== | ==References== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
{{RefHelp}} | |||
<references/> | <references /> | ||
__NOTOC__ | __NOTOC__ | ||
===Categories=== | ===Categories=== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
[[Category:Proteins]] | [[Category:Proteins]] | ||
Latest revision as of 20:26, 17 February 2015
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
HtpG |
|---|---|
| Synonyms |
molecular chaperone HSP90 family[1], B0473[2][1], HtpG[2][1], C62.5[2][1], Hsp90[2][1] , ECK0467, JW0462, b0473 |
| Product description |
Component of molecular chaperone, HSP90 family[3] Heat shock chaperone, HSP90 family; has ATPase activity; binds RpoH; rpoH regulon; dimeric[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006457 |
protein folding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006457 |
protein folding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006457 |
protein folding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006950 |
response to stress |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006950 |
response to stress |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006950 |
response to stress |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0019898 |
extrinsic to membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-9903 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009408 |
response to heat |
IEP: Inferred from Expression Pattern |
P |
complete | ||||
| GO:0051082 |
unfolded protein binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0051082 |
unfolded protein binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0051082 |
unfolded protein binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006974 |
response to DNA damage stimulus |
IEP: Inferred from Expression Pattern |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of molecular chaperone, HSP90 family |
could be indirect |
||
|
Protein |
rpoC |
Experiment(s):EBI-889372 | ||
|
Protein |
hyfG |
Experiment(s):EBI-894374 | ||
|
Protein |
mcrB |
Experiment(s):EBI-894374 | ||
|
Protein |
pepB |
Experiment(s):EBI-894374 | ||
|
Protein |
rplB |
Experiment(s):EBI-894374 | ||
|
Protein |
rpmC |
Experiment(s):EBI-894374 | ||
|
Protein |
rpmG |
Experiment(s):EBI-894374 | ||
|
Protein |
rpsF |
Experiment(s):EBI-894374 | ||
|
Protein |
rpsG |
Experiment(s):EBI-894374 | ||
|
Protein |
ugpB |
Experiment(s):EBI-894374 | ||
|
Protein |
ycbW |
Experiment(s):EBI-894374 | ||
|
Protein |
yeaI |
Experiment(s):EBI-894374 | ||
|
Protein |
yggR |
Experiment(s):EBI-894374 | ||
|
Protein |
hemF |
Experiment(s):EBI-1136800 | ||
|
Protein |
ugpB |
LCMS(ID Probability):99.0 | ||
|
Protein |
hyfG |
LCMS(ID Probability):99.0 | ||
|
Protein |
mcrB |
LCMS(ID Probability):99.0 | ||
|
Protein |
yggR |
LCMS(ID Probability):99.0 | ||
|
Protein |
ycbW |
LCMS(ID Probability):99.0 | ||
|
Protein |
yeaI |
LCMS(ID Probability):99.0 | ||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MKGQETRGFQ SEVKQLLHLM IHSLYSNKEI FLRELISNAS DAADKLRFRA LSNPDLYEGD GELRVRVSFD KDKRTLTISD NGVGMTRDEV IDHLGTIAKS GTKSFLESLG SDQAKDSQLI GQFGVGFYSA FIVADKVTVR TRAAGEKPEN GVFWESAGEG EYTVADITKE DRGTEITLHL REGEDEFLDD WRVRSIISKY SDHIALPVEI EKREEKDGET VISWEKINKA QALWTRNKSE ITDEEYKEFY KHIAHDFNDP LTWSHNRVEG KQEYTSLLYI PSQAPWDMWN RDHKHGLKLY VQRVFIMDDA EQFMPNYLRF VRGLIDSSDL PLNVSREILQ DSTVTRNLRN ALTKRVLQML EKLAKDDAEK YQTFWQQFGL VLKEGPAEDF ANQEAIAKLL RFASTHTDSS AQTVSLEDYV SRMKEGQEKI YYITADSYAA AKSSPHLELL RKKGIEVLLL SDRIDEWMMN YLTEFDGKPF QSVSKVDESL EKLADEVDES AKEAEKALTP FIDRVKALLG ERVKDVRLTH RLTDTPAIVS TDADEMSTQM AKLFAAAGQK VPEVKYIFEL NPDHVLVKRA ADTEDEAKFS EWVELLLDQA LLAERGTLED PNLFIRRMNQ LLVS |
| Length |
624 |
| Mol. Wt |
71.424 kDa |
| pI |
5.0 (calculated) |
| Extinction coefficient |
81,820 (calc based on 18 Y, 10 W, and 0 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
|
Structure figures
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ Chuang, SE & Blattner, FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J. Bacteriol. 175 5242-52 PubMed
- ↑ Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 10.0 10.1 10.2 10.3 10.4 10.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ 11.0 11.1 11.2 11.3 11.4 Macek, B et al. (2008) Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol. Cell Proteomics 7 299-307 PubMed
- ↑ 12.0 12.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0000166 ! nucleotide binding
- GO:0005524 ! ATP binding
- GO:0005829 ! cytosol
- GO:0005886 ! plasma membrane
- GO:0006457 ! protein folding
- GO:0006950 ! response to stress
- GO:0016020 ! membrane
- GO:0019898 ! extrinsic component of membrane
- GO:0009408 ! response to heat
- GO:0051082 ! unfolded protein binding
- GO:0006974 ! cellular response to DNA damage stimulus
- Proteins