metQ:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
DL-methionine transporter subunit<ref name='LIB:Riley_2006'/>, periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B0197<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetQ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaeC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''DL-methionine transporter subunit<ref name='LIB:Riley_2006'/>, periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B0197<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MetQ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YaeC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0197, JW0193, metD, yaeC, b0197''
|-
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="S46aa22e219396"  class=" tableEdit GO_table_product dataTable"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
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GO:0005515
GO:0005886
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|
protein binding
plasma membrane
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|
PMID:16606699
GOA:spkw<br />SP_KW:GO_REF:0000004
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|
IPI: Inferred from Physical Interaction
IEA: Inferred from Electronic Annotation
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|
UniProtKB:P0A6Y8
SP_KW:KW-1003
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|
F
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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transport
transport
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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P
P
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
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complete  
complete  
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amino acid transport
amino acid transport
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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P
P
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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membrane
membrane
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
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complete
|-
|
 
|
GO:0005886
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plasma membrane
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GO_REF:0000004<br />GO_REF:0000023
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-1003<br />SP_SL:SL-0039
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C
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
|
complete  
complete  
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|
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GO:0005515
GO:0031225
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protein binding
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PMID:16606699
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IPI: Inferred from Physical Interaction
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UniProtKB:P0A6Y8
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F
|
Seeded from EcoCyc
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complete
|-
|
 
|
GO:0005886
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plasma membrane
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GO_REF:0000004<br />GO_REF:0000023
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-1003<br />SP_SL:SL-0039
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C
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Seeded from EcoCyc
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complete
|-
|
 
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GO:0006810
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transport
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0813
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P
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Seeded from EcoCyc
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complete
|-
|
 
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GO:0006865
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amino acid transport
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0029
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P
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Seeded from EcoCyc
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complete
|-
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GO:0016020
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membrane
anchored to membrane
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GO_REF:0000004
GO_REF:0000023
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IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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SP_KW:KW-0472
SP_SL:SL-9901
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C
C
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|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
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complete  
complete  


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****************************************************************************************** -->{{Product_interactions_help}}
****************************************************************************************** -->{{Product_interactions_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M46aa22e28906d"  class=" tableEdit Product_interactions_table dataTable"   
|- {{table heading style}}
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1135924<br />  
Experiment(s):EBI-1135924<br />  
|-
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Protein
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yfaY
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PMID:19402753
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LCMS(ID Probability):99.6
|-
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Protein
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araG
|


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PMID:19402753
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LCMS(ID Probability):99.6
|-
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Protein
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yahK
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|
PMID:19402753
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LCMS(ID Probability):99.6
|-
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Protein
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kefF
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|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
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Protein
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gfcA
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|
PMID:19402753
|
LCMS(ID Probability):99.6
 
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****************************************************************************************** -->{{Product_localization_help}}
****************************************************************************************** -->{{Product_localization_help}}
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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-  
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From EcoCyc<ref name='LIB:EcoCyc11.1'/>   
From EcoCyc<ref name='LIB:EcoCyc11.1'/>  
|
   
|-
|
Inner membrane
|
|PMID:12218041
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB1467 EchoLocation:metQ]
|


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****************************************************************************************** -->{{Product_physical_properties_help}}
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!align=left {{table heading style}} |Name
||


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20,400 - 20,525 (calc based on 10 Y, 1 W, and 1 C residues)
20,400 - 20,525 (calc based on 10 Y, 1 W, and 1 C residues)


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****************************************************************************************** -->{{Product_domains_motifs_help}}
****************************************************************************************** -->{{Product_domains_motifs_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="U46aa22e559b87"  class=" tableEdit Product_motif_table dataTable"   
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-  
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[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
|
|
[http://www.uniprot.org/uniprot/P28635#section_features UniProt:P28635]  
[http://www.uniprot.org/uniprot/P28635#section_features UniProt:P28635]
|
|-
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Domain
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33..271
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[http://pfam.janelia.org/family/PF03180 PF03180  NLPA lipoprotein]
|
 
|
PMID:19920124


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||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P28635 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P28635 PSI-PRED (P28635)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P28635 Genomes TO Protein (P28635)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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|- {{table_heading_style}}
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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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*  
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****************************************************************************************** -->{{Gene_accessions_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="I46aa22e6422c2"  class=" tableEdit Gene_accessions_table"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16128190 GI:16128190]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=METQ-MONOMER EcoCyc:METQ-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein/NP_414739.1 GeneID:944893]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0000666
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P28635 UniProtKB/Swiss-Prot:P28635]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11504
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoGene]]
|
|
[[uniprot:P28635|UniProt:P28635]]
EcoGene:EG11504
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[http://pfam.sanger.ac.uk/family?acc=PF03180 PFAM:PF03180]
[http://www.ncbi.nlm.nih.gov/gene?term=944893 GeneID:944893]
|
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_414739 RefSeq:NP_414739]
RegulonDB:ECK120001460
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P28635 ModBase:P28635]
EchoBASE:EB1467
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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[[Category:Proteins]]
[[Category:Proteins]]
[[Category:Complex:L- and D-methionine uptake ABC permease]][[Category:Location:periplasm]]
[[Category:Complex:L- and D-methionine uptake ABC permease]][[Category:Location:periplasm]]
[[Category:Pfam:PF03180_!_NLPA lipoprotein]]

Latest revision as of 20:22, 17 February 2015

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MetQ

Synonyms

DL-methionine transporter subunit[1], periplasmic-binding component of ABC superfamily[1], B0197[2][1], MetD[2][1], MetQ[2][1], YaeC[2][1] , ECK0197, JW0193, metD, yaeC, b0197

Product description

MetQ[2][3];

Component of L- and D-methionine uptake ABC permease[2][3]

L,D-methionine transporter, methionine-binding receptor; lipoprotein; methionine sulfoximine sensitivity[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0006865

amino acid transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0029

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0031225

anchored to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9901

C

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of L- and D-methionine uptake ABC permease

could be indirect

Protein

araG

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

yfaY

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

kefF

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

yahK

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

gfcA

PMID:15690043[5]

Experiment(s):EBI-891576

Protein

dnaK

PMID:16606699[6]

Experiment(s):EBI-1135924

Protein

yfaY

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

araG

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yahK

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

kefF

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

gfcA

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

periplasm

From EcoCyc[3]

Inner membrane

PMID:12218041

EchoLocation:metQ


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MAFKFKTFAA VGALIGSLAL VGCGQDEKDP NHIKVGVIVG AEQQVAEVAQ KVAKDKYGLD
VELVTFNDYV LPNEALSKGD IDANAFQHKP YLDQQLKDRG YKLVAVGNTF VYPIAGYSKK
IKSLDELQDG SQVAVPNDPT NLGRSLLLLQ KVGLIKLKDG VGLLPTVLDV VENPKNLKIV
ELEAPQLPRS LDDAQIALAV INTTYASQIG LTPAKDGIFV EDKESPYVNL IVTREDNKDA
ENVKKFVQAY QSDEVYEAAN KVFNGGAVKG W
Length

271

Mol. Wt

29.431 kDa

pI

5.0 (calculated)

Extinction coefficient

20,400 - 20,525 (calc based on 10 Y, 1 W, and 1 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-22

UniProt Manual:Signal Peptides

UniProt:P28635

Domain

33..271

PF03180 NLPA lipoprotein

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=metQ taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128190

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:944893

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000666

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P28635

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11504

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11504

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:944893

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001460

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1467

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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