sbcC:Quickview: Difference between revisions

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{|   id="C49b024a6d0194"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[sbcC:Gene|''sbcC]]'' (synonyms: ''ECK0391, b0397, JW0387, rmuA'')<ref name='LIB:Riley_2006'/>
''sbcC''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[sbcC:Gene_Product(s)|SbcC product]]<ref name='LIB:Riley_2006'/>: exonuclease, dsDNA, ATP-dependent product, B0397 product
''ECK0391, b0397, JW0387, rmuA''<ref name='LIB:Riley_2006'/>, rmuA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:SbcCD ATP-dependent dsDNA exonuclease|SbcCD ATP-dependent dsDNA exonuclease]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:SbcCD ATP-dependent dsDNA exonuclease|SbcCD ATP-dependent dsDNA exonuclease]]<ref name='LIB:EcoCyc11.1'/>


DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; required for recombinational repair of dsDNA breaks; cosuppressor with sbcB of recB recC mutations; heterodimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''exonuclease, dsDNA, ATP-dependent<ref name='LIB:Riley_2006'/>, B0397<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbcC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0391, JW0387, rmuA, b0397''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=sbcC&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10927]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000916&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=sbcC&loc=MG1655%3A414977..411831,W3110%3A414977..411831,DH10B%3A354308..351162,REL606%3A384176..381030,BW2952%3A314590..317736]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=314590&end=317736&gene=sbcC&aa=mkilslrlknlnslkgewkidftrepfasnglfaitgptgagkttlldaiclalyhetprlsnvsqsqndlmtrdtaeclaevefevkgeayrafwsqnrarnqpdgnlqvprvelarcadgkiladkvkdkleltatltgldygrftrsmllsqgqfaaflnakpkeraelleeltgteiygqisamvfeqhksarteleklqaqasgvtlltpeqvqsltaslqvltdeekqlitaqqqeqqslnwltrqdelqqeasrrqqalqqalaeeekaqpqlaalslaqparnlrphweriaehsaalahirqqieevntrlqstmalrasirhhaakqsaelqqqqqslntwlqehdrfrqwnnepagwraqfsqqtsdrehlrqwqqqlthaeqklnalaaitltltadevatalaqhaeqrplrqhlvalhgqivpqqkrlaqlqvaiqnvtqeqtqrnaalnemrqrykektqqladvkticeqeariktleaqraqlqagqpcplcgstshpaveayqalepgvnqsrllalenevkklgeegatlrgqldaitkqlqrdeneaqslrqdeqaltqqwqavtaslnitlqplddiqpwldaqdeherqlrllsqrhelqgqiaahnqqiiqyqqqieqrqqlllttltgyaltlpqedeeeswlatrqqeaqswqqrqneltalqnriqqltpiletlpqsdelphceetvvlenwrqvheqclalhsqqqtlqqqdvlaaqslqkaqaqfdtalqasvfddqqaflaalmdeqtltqleqlkqnlenqrrqaqtlvtqtaetlaqhqqhrpddglaltvtveqiqqelaqthqklrenttsqgeirqqlkqdadnrqqqqtlmqqiaqmtqqvedwgylnsligskegdkfrkfaqgltldnlvhlanqqltrlhgryllqrkasealevevvdtwqadavrdtrtlsggesflvslalalalsdlvshktridslfldegfgtldsetldtaldaldalnasgktigvishveamkeripvqikvkkinglgysklestfavk]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=sbcC+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=sbcC]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linko a protein. SbcCD limits recombination between short inverted repeats, but is also reported to be required for palindrome-stimulated deletion. SbcCD protein forms a large 1.2 megadalton complex. Second amino acid was sequenced in protein as Gly, but in all DNA samples is a Lys codon.  Coiled coil protein.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

sbcC

Gene Synonym(s)

ECK0391, b0397, JW0387, rmuA[1], rmuA

Product Desc.

ATP-dependent dsDNA exonuclease[2][3];

Component of SbcCD ATP-dependent dsDNA exonuclease[3]

DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; required for recombinational repair of dsDNA breaks; cosuppressor with sbcB of recB recC mutations; heterodimeric[4]

Product Synonyms(s)

exonuclease, dsDNA, ATP-dependent[1], B0397[2][1], SbcC[2][1] , ECK0391, JW0387, rmuA, b0397

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): sbcC[2]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linko a protein. SbcCD limits recombination between short inverted repeats, but is also reported to be required for palindrome-stimulated deletion. SbcCD protein forms a large 1.2 megadalton complex. Second amino acid was sequenced in protein as Gly, but in all DNA samples is a Lys codon. Coiled coil protein.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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