yrfF:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YrfF

Synonyms

predicted inner membrane protein[1], B3398[2][1], YrfF[2][1] , ECK3385, igaA, JW3361, mucM, umoB, b3398

Product description

predicted inner membrane protein[2]; putative dehydrogenase[3]

Function unknown, deletion cause mucoidy; probable integral inner membrane protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0009276

Gram-negative-bacterium-type cell wall

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010771

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010771

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 5 predicted transmembrane domains

Daley et al. (2005) [5]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSTIVIFLAA LLACSLLAGW LIKVRSRRRQ LPWTNAFADA QTRKLTPEER SAVENYLESL
TQVLQVPGPT GASAAPISLA LNAESNNVMM LTHAITRYGI STDDPNKWRY YLDSVEVHLP
PFWEQYINDE NTVELIHTDS LPLVISLNGH TLQEYMQETR SYALQPVPST QASIRGEESE
QIELLNIRKE THEEYALSRP RGLREALLIV ASFLMFFFCL ITPDVFVPWL AGGALLLLGA
GLWGLFAPPA KSSLREIHCL RGTPRRWGLF GENDQEQINN ISLGIIDLVY PAHWQPYIAQ
DLGQQTDIDI YLDRHVVRQG RYLSLHDEVK NFPLQHWLRS TIIAAGSLLV LFMLLFWIPL
DMPLKFTLSW MKGAQTIEAT SVKQLADAGV RVGDTLRISG TGMCNIRTSG TWSAKTNSPF
LPFDCSQIIW NDARSLPLPE SELVNKATAL TEAVNRQLHP KPEDESRVSA SLRSAIQKSG
MVLLDDFGDI VLKTADLCSA KDDCVRLKNA LVNLGNSKDW DALVKRANAG KLDGVNVLLR
PVSAESLDNL VATSTAPFIT HETARAAQSL NSPAPGGFLI VSDEGSDFVD QPWPSASLYD
YPPQEQWNAF QKLAQMLMHT PFNAEGIVTK IFTDANGTQH IGLHPIPDRS GLWRYLSTTL
LLLTMLGSAI YNGVQAWRRY QRHRTRMMEI QAYYESCLNP QLITPSESLI E
Length

711

Mol. Wt

79.492 kDa

pI

6.1 (calculated)

Extinction coefficient

127,310 - 128,310 (calc based on 19 Y, 18 W, and 8 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

1..707

PF07095 Intracellular growth attenuator protein IgaA

PMID:19920124[6]

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<motif_map/>

tmhmm.php?gene=yrfF&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yrfF taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131275

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947905

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011090

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P45800

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7741

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12927

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947905

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004284

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2763

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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