yjjX:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YjjX

Synonyms

thiamin metabolism associated protein [1], B4394 [2][1], YjjX [2][1] , ECK4386, JW5801, b4394

Product description

ITPase/XTPase[2][3]

Inosine/xanthosine triphosphatase; may be involved in detoxifying ITP and XTP; dimeric;[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006772

thiamin metabolic process

PMID:15292217[5]

EXP: Inferred from Experiment

P

complete

GO:0017111

nucleoside-triphosphatase activity

PMID:16216582[6]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dnaN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yihX

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):8.670415

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MLIMHQVVCA TTNPAKIQAI LQAFHEIFGE GSCHIASVAV ESGVPEQPFG SEETRAGARN
RVANARRLLP EADFWVAIEA GIDGDSTFSW VVIENASQRG EARSATLPLP AVILEKVREG
EALGPVMSRY TGIDEIGRKE GAIGVFTAGK LTRASVYHQA VILALSPFHN AVY
Length

173

Mol. Wt

18.569 kDa

pI

6.0 (calculated)

Extinction coefficient

15,470 - 15,720 (calc based on 3 Y, 2 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

7..170

PF01931 Protein of unknown function DUF84

PMID:19920124[8]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yjjX taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111748

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948919

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0014411

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P39411

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12600

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12600

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948919

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002327

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2485

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Lawhorn, BG et al. (2004) A genetic screen for the identification of thiamin metabolic genes. J. Biol. Chem. 279 43555-9 PubMed
  6. ↑ Zheng, J et al. (2005) Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis. Structure 13 1511-20 PubMed
  7. ↑ 7.0 7.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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