yhjK:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YhjK

Synonyms

predicted diguanylate cyclase[1], B3529[2][1], YhjK[2][1] , ECK3514, JW5943, b3529

Product description

predicted zinc-dependent peptidase[2][3]

Putative c-di-GMP dual activity enzyme, function unknown; expressed protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003660

F

Seeded from EcoCyc (v14.0)

complete

GO:0007165

signal transduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003660

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003660

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 3 predicted transmembrane domains

Daley et al. (2005) [5]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAMVAAVVLV FVFIFCTVLL FHLVQQNRYN TATQLESIAR SVREPLSSAI LKGDIPEAEA
ILASIKPAGV VSRADVVLPN QFQALRKSFI PERPVPVMVT RLFELPVQIS LGVYSLERPA
NPQPIAYLVL QADSFRMYKF VMSTLSTLVT IYLLLSLILT VAISWCINRL ILHPLRNIAR
ELNAIPAKEL VGHQLALPRL HQDDEIGMLV RSYNLNQQLL QRHYEEQNEN AMRFPVSDLP
NKALLMEMLE QVVARKQTTA LMIITCETLR DTAGVLKEAQ REILLLTLVE KLKSVLSPRM
ILAQISGYDF AVIANGVQEP WHAITLGQQV LTIMSERLPI ERIQLRPHCS IGVAMFYGDL
TAEQLYSRAI SAAFTARHKG KNQIQFFDPQ QMEAAQKRLT EESDILNALE NHQFAIWLQP
QVEMTSGKLV SAEVLLRIQQ PDGSWDLPDG LIDRIECCGL MVTVGHWVLE ESCRLLAAWQ
ERGIMLPLSV NLSALQLMHP NMVADMLELL TRYRIQPGTL ILEVTESRRI DDPHAAVAIL
RPLRNAGVRV ALDDFGMGYA GLRQLQHMKS LPIDVLKIDK MFVEGLPGDS SMIAAIIMLA
QSLNLQMIAE GVETEAQRDW LAKAGVGIAQ GFLFARPLPI EIFEESYLEE K
Length

651

Mol. Wt

73.082 kDa

pI

6.1 (calculated)

Extinction coefficient

57,870 - 58,745 (calc based on 13 Y, 7 W, and 7 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

231..383

PF00990 GGDEF domain

PMID:19920124[6]

Domain

149..222

PF00672 HAMP domain

PMID:19920124[6]

Domain

402..637

PF00563 EAL domain

PMID:19920124[6]

<motif_map/>

tmhmm.php?gene=yhjK&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yhjK taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:226524755

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948048

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011533

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P37649

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12256

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12256

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948048

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002137

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2165

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. 6.0 6.1 6.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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