yfgF:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YfgF

Synonyms

predicted inner membrane protein[1], B2503[2][1], YfgF[2][1] , ECK2499, JW2488, b2503

Product description

predicted inner membrane protein[2][3]

Putative c-di-GMP dual activity enzyme, function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 9 predicted transmembrane domains

Daley et al. (2005) [5]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MKLNATYIKI RDKWWGLPLF LPSLILPIFA HINTFAHISS GEVFLFYLPL ALMISMMMFF
SWAALPGIAL GIFVRKYAEL GFYETLSLTA NFIIIIILCW GGYRVFTPRR NNVSHGDTRL
ISQRIFWQIV FPATLFLILF QFAAFVGLLA SRENLVGVMP FNLGTLINYQ ALLVGNLIGV
PLCYFIIRVV RNPFYLRSYY SQLKQQVDAK VTKKEFALWL LALGALLLLL CMPLNEKSTI
FSTNYTLSLL LPLMMWGAMR YGYKLISLLW AVVLMISIHS YQNYIPIYPG YTTQLTITSS
SYLVFSFIVN YMAVLATRQR AVVRRIQRLA YVDPVVHLPN VRALNRALRD APWSALCYLR
IPGMEMLVKN YGIMLRIQYK QKLSHWLSPL LEPGEDVYQL SGNDLALRLN TESHQERITA
LDSHLKQFRF FWDGMPMQPQ IGVSYCYVRS PVNHIYLLLG ELNTVAELSI VTNAPENMQR
RGAMYLQREL KDKVAMMNRL QQALEHNHFF LMAQPITGMR GDVYHEILLR MKGENDELIS
PDSFLPVAHE FGLSSSIDMW VIEHTLQFMA ENRAKMPAHR FAINLSPTSV CQARFPVEVS
QLLAKYQIEA WQLIFEVTES NALTNVKQAQ ITLQHLQELG CQIAIDDFGT GYASYARLKN
VNADLLKIDG SFIRNIVSNS LDYQIVASIC HLARMKKMLV VAEYVENEEI REAVLSLGID
YMQGYLIGKP QPLIDTLNEI EPIRESA
Length

747

Mol. Wt

85.611 kDa

pI

9.0 (calculated)

Extinction coefficient

125,140 - 126,140 (calc based on 36 Y, 13 W, and 8 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

497..730

PF00563 EAL domain

PMID:19920124[6]

Domain

15..320

PF05231 MASE1

PMID:19920124[6]

<motif_map/>

tmhmm.php?gene=yfgF&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yfgF taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130428

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946968

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008240

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P77172

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7314

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14202

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946968

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003886

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3954

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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