yfaL:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YfaL

Synonyms

adhesin[1], B2233[2][1], YfaJ[2][1], YfaK[2][1], YfaF[2][1], YfaL[2][1] , ECK2225, JW2227, yfaF, yfaJ, yfaK, b2233

Product description

potential adhesin[2][3]

Probable OM autotransporter adhesin, function unknown; overexpression increases adhesion and biofilm formation[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019867

outer membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006315

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

metL

PMID:16606699[5]

Experiment(s):EBI-1142273

Protein

alaS

PMID:16606699[5]

Experiment(s):EBI-1142273

Protein

clpB

PMID:16606699[5]

Experiment(s):EBI-1142273

Protein

mukB

PMID:16606699[5]

Experiment(s):EBI-1142273

Protein

rpsB

PMID:16606699[5]

Experiment(s):EBI-1142273

Protein

rplF

PMID:16606699[5]

Experiment(s):EBI-1142273

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MRIIFLRKEY LSLLPSMIAS LFSANGVAAV TDSCQGYDVK ASCQASRQSL SGITQDWSIA
DGQWLVFSDM TNNASGGAVF LQQGAEFSLL PENETGMTLF ANNTVTGEYN NGGAIFAKEN
STLNLTDVIF SGNVAGGYGG AIYSSGTNDT GAVDLRVTNA MFRNNIANDG KGGAIYTINN
DVYLSDVIFD NNQAYTSTSY SDGDGGAIDV TDNNSDSKHP SGYTIVNNTA FTNNTAEGYG
GAIYTNSVTA PYLIDISVDD SYSQNGGVLV DENNSAAGYG DGPSSAAGGF MYLGLSEVTF
DIADGKTLVI GNTENDGAVD SIAGTGLITK TGSGDLVLNA DNNDFTGEMQ IENGEVTLGR
SNSLMNVGDT HCQDDPQDCY GLTIGSIDQY QNQAELNVGS TQQTFVHALT GFQNGTLNID
AGGNVTVNQG SFAGIIEGAG QLTIAQNGSY VLAGAQSMAL TGDIVVDDGA VLSLEGDAAD
LTALQDDPQS IVLNGGVLDL SDFSTWQSGT SYNDGLEVSG SSGTVIGSQD VVDLAGGDNL
HIGGDGKDGV YVVVDASDGQ VSLANNNSYL GTTQIASGTL MVSDNSQLGD THYNRQVIFT
DKQQESVMEI TSDVDTRSDA AGHGRDIEMR ADGEVAVDAG VDTQWGALMA DSSGQHQDEG
STLTKTGAGT LELTASGTTQ SAVRVEEGTL KGDVADILPY ASSLWVGDGA TFVTGADQDI
QSIDAISSGT IDISDGTVLR LTGQDTSVAL NASLFNGDGT LVNATDGVTL TGELNTNLET
DSLTYLSNVT VNGNLTNTSG AVSLQNGVAG DTLTVNGDYT GGGTLLLDSE LNGDDSVSDQ
LVMNGNTAGN TTVVVNSITG IGEPTSTGIK VVDFAADPTQ FQNNAQFSLA GSGYVNMGAY
DYTLVEDNND WYLRSQEVTP PSPPDPDPTP DPDPTPDPDP TPDPEPTPAY QPVLNAKVGG
YLNNLRAANQ AFMMERRDHA GGDGQTLNLR VIGGDYHYTA AGQLAQHEDT STVQLSGDLF
SGRWGTDGEW MLGIVGGYSD NQGDSRSNMT GTRADNQNHG YAVGLTSSWF QHGNQKQGAW
LDSWLQYAWF SNDVSEQEDG TDHYHSSGII ASLEAGYQWL PGRGVVIEPQ AQVIYQGVQQ
DDFTAANRAR VSQSQGDDIQ TRLGLHSEWR TAVHVIPTLD LNYYHDPHST EIEEDGSTIS
DDAVKQRGEI KVGVTGNISQ RVSLRGSVAW QKGSDDFAQT AGFLSMTVKW
Length

1,250

Mol. Wt

131.151 kDa

pI

3.8 (calculated)

Extinction coefficient

150,580 - 151,080 (calc based on 42 Y, 16 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-23

UniProt Manual:Signal Peptides

UniProt:P45508

Domain

982..1239

PF03797 Autotransporter beta-domain

PMID:19920124[6]

Domain

127..145

PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP)

PMID:19920124[6]

Domain

186..211

PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP)

PMID:19920124[6]

Domain

222..246

PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP)

PMID:19920124[6]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yfaL taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130168

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946595

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007377

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P45508

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12850

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12850

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946595

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002399

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2695

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. 6.0 6.1 6.2 6.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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