yegH:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YegH

Synonyms

fused predicted membrane protein[1], predicted membrane protein[1], B2063[2][1], YegH[2][1] , ECK2057, JW5336, b2063

Product description

putative transport protein[2][3]

Function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005496

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpmB

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

rplS

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

rpsP

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

rpsT

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

hns

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

rplD

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

lpcA

PMID:19402753[5]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 7 predicted transmembrane domains

Daley et al. (2005) [6]

plasma membrane


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MPRFIHDRIV TFVIQRIGFV LTMEWIADPS IWAGLITLIV IELVLGIDNL VFIAILAEKL
PPKQRDRARV TGLLLAMLMR LLLLASISWL VTLTQPLFSF RSFTFSARDL IMLFGGFFLL
FKATMELNER LEGKDSNNPT QRKGAKFWGV VTQIVVLDAI FSLDSVITAV GMVDHLLVMM
AAVVIAISLM LMASKPLTQF VNSHPTIVIL CLSFLLMIGF SLVAEGFGFV IPKGYLYAAI
GFSVMIEALN QLAIFNRRRF LSANQTLRQR TTEAVMRLLS GQKEDAELDA ETASMLVDHG
NQQIFNPQER RMIERVLNLN QRTVSSIMTS RHDIEHIDLN APEEEIRQLL ERNQHTRLVV
TDGDDAEDLL GVVHVIDLLQ QSLRGEPLNL RVLIRQPLVF PETLPLLPAL EQFRNARTHF
AFVVDEFGSV EGIVTLSDVT ETIAGNLPNE VEEIDARHDI QKNADGSWTA NGHMPLEDLV
QYVPLPLDEK REYHTIAGLL MEYLQRIPKP GEEVQVGDYL LKTLQVESHR VQKVQIIPLR
KDGEMEYEV
Length

549

Mol. Wt

62.092 kDa

pI

5.3 (calculated)

Extinction coefficient

37,930 - 38,055 (calc based on 7 Y, 5 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

302..361

PF00571 CBS domain

PMID:19920124[7]

Domain

368..423

PF00571 CBS domain

PMID:19920124[7]

Domain

439..518

PF03471 Transporter associated domain

PMID:19920124[7]

Domain

14..204

PF03741 Integral membrane protein TerC family

PMID:19920124[7]

<motif_map/>

tmhmm.php?gene=yegH&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yegH taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111378

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946566

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006830

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76389

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7108

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14051

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946566

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003694

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3804

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  6. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  7. 7.0 7.1 7.2 7.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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