yeaE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YeaE

Synonyms

predicted oxidoreductase[1], YeaE[2][1], B1781[2][1] , ECK1779, JW1770, b1781

Product description

methylglyoxal reductase[2][3]

Aldo-keto reductase, methylglyoxal to acetol; NADPH-dependent[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001395

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020471

F

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001395

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020471

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

nadE

PMID:16606699[5]

Experiment(s):EBI-1140791

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1140791

Protein

pheA

PMID:16606699[5]

Experiment(s):EBI-1140791

Protein

napC

PMID:16606699[5]

Experiment(s):EBI-1140791
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MQQKMIQFSG DVSLPAVGQG TWYMGEDASQ RKTEVAALRA GIELGLTLID TAEMYADGGA
EKVVGEALTG LREKVFLVSK VYPWNAGGQK AINACEASLR RLNTDYLDLY LLHWSGSFAF
EETVAAMEKL IAQGKIRRWG VSNLDYADMQ ELWQLPGGNQ CATNQVLYHL GSRGIEYDLL
PWCQQQQMPV MAYSPLAQAG RLRNGLLKNA VVNEIAHAHN ISAAQVLLAW VISHQGVMAI
PKAATIAHVQ QNAAVLEVEL SSAELAMLDK AYPAPKGKTA LDMV
Length

284

Mol. Wt

30.986 kDa

pI

6.0 (calculated)

Extinction coefficient

53,400 - 53,775 (calc based on 10 Y, 7 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

16..273

PF00248 Aldo/keto reductase family

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yeaE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129735

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946302

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0005925

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76234

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6967

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13491

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946302

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003554

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3264

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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