ybbW:Gene Product(s)

Standard name	YbbW
Synonyms	predicted allantoin transporter^[1], B0511^[2]^[1], AllP^[2]^[1], YbbW^[2]^[1] , allP, ECK0504, glxB2, JW0499, b0511
Product description	YbbW NCS1 Transporter^[2]^[3] Probable allantoin permease, glyoxylate-inducible or allantoin-inducible (anaerobic)^[4]
EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005274	allantoin uptake transmembrane transporter activity	PMID:10601204^[5]	ISS: Inferred from Sequence or Structural Similarity		F	Seeded from EcoCyc (v14.0)	Missing: with/from
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C	Seeded from EcoCyc (v14.0)	complete
	GO:0006144	purine base metabolic process	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0659	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006810	transport	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P	Seeded from EcoCyc (v14.0)	complete
	GO:0015205	nucleobase transmembrane transporter activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001248	F	Seeded from EcoCyc (v14.0)	complete
	GO:0015205	nucleobase transmembrane transporter activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012681	F	Seeded from EcoCyc (v14.0)	complete
	GO:0015720	allantoin transport	PMID:10601204^[5]	ISS: Inferred from Sequence or Structural Similarity		P	Seeded from EcoCyc (v14.0)	Missing: with/from
	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001248	P	Seeded from EcoCyc (v14.0)	complete
	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012681	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001248	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012681	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016021	integral to membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-9909	C	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001248	P	Seeded from EcoCyc (v14.0)	complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012681	P	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
plasma membrane	C-terminus localized in the cytoplasm with 12 predicted transmembrane domains	Daley et al. (2005) ^[6]
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MVGGFFILGL STFSIMLAII LSAFFIAAVM VLNGAAGSKY GVPFAMILRA SYGVRGALFP GLLRGGIAAI MWFGLQCYAG SLACLILIGK IWPGFLTLGG DFTLLGLSLP GLITFLIFWL VNVGIGFGGG KVLNKFTAIL NPCIYIVFGG MAIWAISLVG IGPIFDYIPS GIQKAENGGF LFLVVINAVV AVWAAPAVSA SDFTQNAHSF REQALGQTLG LVVAYILFAV AGVCIIAGAS IHYGADTWNV LDIVQRWDSL FASFFAVLVI LMTTISTNAT GNIIPAGYQI AAIAPTKLTY KNGVLIASII SLLICPWKLM ENQDSIYLFL DIIGGMLGPV IGVMMAHYFV VMRGQINLDE LYTAPGDYKY YDNGFNLTAF SVTLVAVILS LGGKFIHFME PLSRVSWFVG VIVAFAAYAL LKKRTTAEKT GEQKTIG
Length	437
Mol. Wt	46.684 kDa
pI	8.7 (calculated)
Extinction coefficient	73,340 - 73,965 (calc based on 16 Y, 9 W, and 5 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	19..457	PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin		PMID:19920124^[7]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure
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Structures

<beststructure> gene=ybbW taxon=562,83333 </beststructure>

Models

View models at:

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</protect>

Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:90111144	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:945138	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0001764	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P75712	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:G6280	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG13618	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:945138	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120002888	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB3383	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 Cusa, E et al. (1999) Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli. J. Bacteriol. 181 7479-84 PubMed
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

ybbW:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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