yajO:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YajO

Synonyms

predicted oxidoreductase, NAD(P)-binding[1], YajO[2][1], B0419[2][1] , ECK0413, JW0409, b0419

Product description

predicted oxidoreductase, NAD(P)-binding[2]; putative NAD(P)H-dependent xylose reductase[3]

2-carboxybenzaldehyde reductase, function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001395

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020471

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001395

P

Seeded from EcoCyc (v14.0)

complete

GO:0006772

thiamin metabolic process

PMID:15292217[5]

EXP: Inferred from Experiment

P

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020471

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

hflB

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

prpB

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

slyD

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

lon

PMID:16606699[6]

Experiment(s):EBI-1136531

Protein

srlD

PMID:19402753[7]

LCMS(ID Probability):98.5

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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MTGVNECSRS TCNLKYDEYS RSGSMQYNPL GKTDLRVSRL CLGCMTFGEP DRGNHAWTLP
EESSRPIIKR ALEGGINFFD TANSYSDGSS EEIVGRALRD FARREDVVVA TKVFHRVGDL
PEGLSRAQIL RSIDDSLRRL GMDYVDILQI HRWDYNTPIE ETLEALNDVV KAGKARYIGA
SSMHASQFAQ ALELQKQHGW AQFVSMQDHY NLIYREEERE MLPLCYQEGV AVIPWSPLAR
GRLTRPWGET TARLVSDEVG KNLYKESDEN DAQIAERLTG VSEELGATRA QVALAWLLSK
PGIAAPIIGT SREEQLDELL NAVDITLKPE QIAELETPYK PHPVVGFK
Length

348

Mol. Wt

39.09 kDa

pI

5.1 (calculated)

Extinction coefficient

50,880 - 51,505 (calc based on 12 Y, 6 W, and 5 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

15..316

PF00248 Aldo/keto reductase family

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yajO taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111130

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946903

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001457

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P77735

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6236

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13611

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946903

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002847

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3377

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Lawhorn, BG et al. (2004) A genetic screen for the identification of thiamin metabolic genes. J. Biol. Chem. 279 43555-9 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 6.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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