yafO:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

YafO

Synonyms

predicted toxin of the YafO-YafN toxin-antitoxin system[1], B0233[2][1], YafO[2][1] , ECK0234, JW0223, b0233

Product description

conserved protein with a possible role in spontaneous mutagenesis; toxin of a putative toxin-antitoxin pair[2][3]

Possible toxin, function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0017148

negative regulation of translation

PMID:19617347[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043023

ribosomal large subunit binding

PMID:19617347[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MRVFKTKLIR LQLTAEELDA LTADFISYKR DGVLPDIFGR DALYDDSFTW PLIKFERVAH
IHLANENNPF PPQLRQFSRT NDEAHLVYCQ GAFDEQAWLL IAILKPEPHK LARDNNQMHK
IGKMAEAFRM RF
Length

132

Mol. Wt

15.488 kDa

pI

7.6 (calculated)

Extinction coefficient

15,470 - 15,595 (calc based on 3 Y, 2 W, and 1 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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Structure
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Structures

<beststructure> gene=yafO taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128219

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:944916

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000795

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:Q47157

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6117

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13152

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:944916

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002737

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2946

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Zhang, Y et al. (2009) Characterization of YafO, an Escherichia coli toxin. J. Biol. Chem. 284 25522-31 PubMed

Categories

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