xapA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

XapA

Synonyms

purine nucleoside phosphorylase II[1], B2407[2][1], PndA[2][1], XapA[2][1] , ECK2401, JW2398, pndA, b2407

Product description

XapA[2][3];

Component of xanthosine phosphorylase[2][3]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0005737

cytoplasm

PMID:15808857[4]

IDA: Inferred from Direct Assay

C

complete

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

PMID:7559336[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process

PMID:7559336[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0004731

purine-nucleoside phosphorylase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011268

F

Seeded from EcoCyc (v14.0)

complete

GO:0004731

purine-nucleoside phosphorylase activity

PMID:15808857[4]

IDA: Inferred from Direct Assay

F

complete

GO:0009116

nucleoside metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000845

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of xanthosine phosphorylase

could be indirect

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1142735

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1142735

Protein

prs

PMID:16606699[6]

Experiment(s):EBI-1142735

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSQVQFSHNP LFCIDIIKTY KPDFTPRVAF ILGSGLGALA DQIENAVAIS YEKLPGFPVS
TVHGHAGELV LGHLQGVPVV CMKGRGHFYE GRGMTIMTDA IRTFKLLGCE LLFCTNAAGS
LRPEVGAGSL VALKDHINTM PGTPMVGLND DRFGERFFSL ANAYDAEYRA LLQKVAKEEG
FPLTEGVFVS YPGPNFETAA EIRMMQIIGG DVVGMSVVPE VISARHCDLK VVAVSAITNM
AEGLSDVKLS HAQTLAAAEL SKQNFINLIC GFLRKIA
Length

277

Mol. Wt

29.834 kDa

pI

6.5 (calculated)

Extinction coefficient

8,940 - 9,690 (calc based on 6 Y, 0 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

27..274

PF01048 Phosphorylase superfamily

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=xapA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130333

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946878

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007927

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P45563

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G85

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG20250

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946878

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004462

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4152

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 Dandanell, G et al. (2005) Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene. J. Mol. Biol. 348 113-25 PubMed
  5. 5.0 5.1 Seeger, C et al. (1995) Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli. J. Bacteriol. 177 5506-16 PubMed
  6. 6.0 6.1 6.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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