uxaA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

UxaA

Synonyms

altronate hydrolase[1], B3091[2][1], YgjW[2][1], UxaA[2][1] , ECK3082, JW3062, ygjW, b3091

Product description

D-Altronate hydrolase (hydratase), Fe(2)-requiring; galacturonate branch of hexuronate pathway[3]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0008789

altronate dehydratase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.2.1.7

F

Seeded from EcoCyc (v14.0)

complete

GO:0030145

manganese ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0464

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

stfR

PMID:16606699[4]

Experiment(s):EBI-1144792

Protein

pheT

PMID:16606699[4]

Experiment(s):EBI-1144792

Protein

ybcS

PMID:16606699[4]

Experiment(s):EBI-1144792

Protein

lhr

PMID:16606699[4]

Experiment(s):EBI-1144792

Protein

yidR

PMID:19402753[5]

MALDI(Z-score):37.785561

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MQYIKIHALD NVAVALADLA EGTEVSVDNQ TVTLRQDVAR GHKFALTDIA KGANVIKYGL
PIGYALADIA AGVHVHAHNT RTNLSDLDQY RYQPDFQDLP AQAADREVQI YRRANGDVGV
RNELWILPTV GCVNGIARQI QNRFLKETNN AEGTDGVFLF SHTYGCSQLG DDHINTRTML
QNMVRHPNAG AVLVIGLGCE NNQVAAFRET LGDIDPERVH FMICQQQDDE IEAGIEHLHQ
LYNVMRNDKR EPGKLSELKF GLECGGSDGL SGITANPMLG RFSDYVIANG GTTVLTEVPE
MFGAEQLLMD HCRDEATFEK LVTMVNDFKQ YFIAHDQPIY ENPSPGNKAG GITTLEDKSL
GCTQKAGSSV VVDVLRYGER LKTPGLNLLS APGNDAVATS ALAGAGCHMV LFSTGRGTPY
GGFVPTVKIA TNSELAAKKK HWIDFDAGQL IHGKAMPQLL EEFIDTIVEF ANGKQTCNER
NDFRELAIFK SGVTL
Length

495

Mol. Wt

54.092 kDa

pI

5.4 (calculated)

Extinction coefficient

30,370 - 31,495 (calc based on 13 Y, 2 W, and 9 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

104..495

PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus

PMID:19920124[6]

Domain

10..81

PF08666 SAF domain

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=uxaA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130986

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947603

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010164

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P42604

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12734

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12734

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947603

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002375

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2592

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  5. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  6. ↑ 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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