umuC:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
umuC |
|---|---|
| Gene Synonym(s) |
ECK1172, b1184, JW1173, uvm[1], uvm |
| Product Desc. |
SOS mutagenesis and repair[2][3]; Component of DNA polymerase V[3] DNA polymerase V subunit, capable of translesion synthesis; polymerase activity subunit; UV induction of mutations, error-prone repair; forms complex with UmuD and UmuD'; intrinsic AP lyase activity; lexA regulon[4] |
| Product Synonyms(s) |
DNA polymerase V, subunit C[1], B1184[2][1], Uvm[2][1], UmuC[2][1] , ECK1172, JW1173, uvm, b1184 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
ATPgammaS inhibits UmuC activity. Lesion bypass requires the assembly of RecA nucleoprotein filaments, thus single-stranded gaps of greater than 100 nucleotides are required.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
