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References Suggestions


Standard Name


Gene Synonym(s)

ECK1172, b1184, JW1173, uvm[1], uvm

Product Desc.

SOS mutagenesis and repair[2][3];

Component of DNA polymerase V[3]

DNA polymerase V subunit, capable of translesion synthesis; polymerase activity subunit; UV induction of mutations, error-prone repair; forms complex with UmuD and UmuD'; intrinsic AP lyase activity; lexA regulon[4]

Product Synonyms(s)

DNA polymerase V, subunit C[1], B1184[2][1], Uvm[2][1], UmuC[2][1] , ECK1172, JW1173, uvm, b1184

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): umuDC[2], OP00250

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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ATPgammaS inhibits UmuC activity. Lesion bypass requires the assembly of RecA nucleoprotein filaments, thus single-stranded gaps of greater than 100 nucleotides are required.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.