torD:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

TorD

Synonyms

chaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I[1], B0998[2][1], TorD[2][1] , ECK0989, JW0983, b0998

Product description

chaperone protein for trimethylamine-N-oxide oxidoreductase I[2][3]

Redox enzyme maturation protein (REMP) for TorA; cytoplasmic chaperone for TorA activation; protects TorA TAT signal peptide from degradation[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01150

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006457

protein folding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01150

P

Seeded from EcoCyc (v14.0)

complete

GO:0008940

nitrate reductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003765

F

Seeded from EcoCyc (v14.0)

complete

GO:0009325

nitrate reductase complex

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003765

C

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003765

P

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

PMID:9632735[5]

IDA: Inferred from Direct Assay

C

complete

GO:0042277

peptide binding

PMID:18522945[6]

IMP: Inferred from Mutant Phenotype

F

TorD binds the TorA signal sequence (Figure 3).

complete

GO:0005515

protein binding

PMID:18522945[6]

IPI: Inferred from Physical Interaction

EcoliWiki:mobA


F

complete

GO:0043546

molybdopterin cofactor binding

PMID:18522945[6]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0051604

protein maturation

PMID:15723832[7]

IEP: Inferred from Expression Pattern

P

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplW

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

groS

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

pta

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

yajQ

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):29.816468

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MTTLTAQQIA CVYAWLAQLF SRELDDEQLT QIASAQMAEW FSLLKSEPPL TAAVNELENR
IATLTVRDDA RLELAADFCG LFLMTDKQAA LPYASAYKQD EQEIKRLLVE AGMETSGNFN
EPADHLAIYL ELLSHLHFSL GEGTVPARRI DSLRQKTLTA LWQWLPEFVA RCRQYDSFGF
YAALSQLLLV LVECDHQNR
Length

199

Mol. Wt

22.573 kDa

pI

4.6 (calculated)

Extinction coefficient

30,940 - 31,440 (calc based on 6 Y, 4 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

14..172

PF02613 Nitrate reductase delta subunit

PMID:19920124[9]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=torD taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128964

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945625

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003374

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P36662

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12195

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12195

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945625

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002084

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2112

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Pommier, J et al. (1998) TorD, a cytoplasmic chaperone that interacts with the unfolded trimethylamine N-oxide reductase enzyme (TorA) in Escherichia coli. J. Biol. Chem. 273 16615-20 PubMed
  6. ↑ 6.0 6.1 6.2 Genest, O et al. (2008) Dedicated metallochaperone connects apoenzyme and molybdenum cofactor biosynthesis components. J. Biol. Chem. 283 21433-40 PubMed
  7. ↑ Genest, O et al. (2005) TorD, an essential chaperone for TorA molybdoenzyme maturation at high temperature. J. Biol. Chem. 280 15644-8 PubMed
  8. ↑ 8.0 8.1 8.2 8.3 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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