tdcD:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

TdcD

Synonyms

propionate kinase/acetate kinase C, anaerobic[1], B3115[2][1], YhaA[2][1], TdcD[2][1] , ECK3104, JW5806, yhaA, b3115

Product description

Propionate kinase, anaerobic; non-essential gene[3]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000890

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00020

C

Seeded from EcoCyc (v14.0)

complete

GO:0008776

acetate kinase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00020

F

Seeded from EcoCyc (v14.0)

complete

GO:0008980

propionate kinase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.2.15

F

Seeded from EcoCyc (v14.0)

complete

GO:0016310

phosphorylation

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00020

P

Seeded from EcoCyc (v14.0)

complete

GO:0016310

phosphorylation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000890

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

lysS

PMID:15690043[4]

Experiment(s):EBI-886684, EBI-890312

Protein

tufA

PMID:15690043[4]

Experiment(s):EBI-886684

Protein

glf

PMID:15690043[4]

Experiment(s):EBI-893053

Protein

glf

PMID:19402753[5]

LCMS(ID Probability):99.6

Protein

tufB

PMID:19402753[5]

MALDI(Z-score):23.149329

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MRKEMNEFPV VLVINCGSSS IKFSVLDASD CEVLMSGIAD GINSENAFLS VNGGEPAPLA
HHSYEGALKA IAFELEKRNL NDSVALIGHR IAHGGSIFTE SAIITDEVID NIRRVSPLAP
LHNYANLSGI ESAQQLFPGV TQVAVFDTSF HQTMAPEAYL YGLPWKYYEE LGVRRYGFHG
TSHRYVSQRA HSLLNLAEDD SGLVVAHLGN GASICAVRNG QSVDTSMGMT PLEGLMMGTR
SGDVDFGAMS WVASQTNQSL GDLERVVNKE SGLLGISGLS SDLRVLEKAW HEGHERAQLA
IKTFVHRIAR HIAGHAASLR RLDGIIFTGG IGENSSLIRR LVMEHLAVLG LEIDTEMNNR
SNSCGERIVS SENARVICAV IPTNEEKMIA LDAIHLGKVN APAEFA
Length

406

Mol. Wt

43.928 kDa

pI

5.9 (calculated)

Extinction coefficient

28,420 - 29,045 (calc based on 8 Y, 3 W, and 5 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

6..387

PF00871 Acetokinase family

PMID:19920124[6]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=tdcD taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:145698313

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947635

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010245

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P11868

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11172

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11172

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947635

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001154

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1159

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. 4.0 4.1 4.2 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  5. 5.0 5.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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