sseA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

SseA

Synonyms

3-mercaptopyruvate sulfurtransferase[1], B2521[2][1], SseA[2][1] , ECK2517, JW2505, b2521

Product description

EG11600[2][3]

3-mercaptopyruvate sulfurtransferase; enhances serine sensitivity (inhibits homoserine deHase) on lactate; rhodanese-like protein[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004792

thiosulfate sulfurtransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001307

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0008272

sulfate transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001307

P

Seeded from EcoCyc (v14.0)

complete

GO:0016784

3-mercaptopyruvate sulfurtransferase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.8.1.2

F

Seeded from EcoCyc (v14.0)

complete

GO:0016784

3-mercaptopyruvate sulfurtransferase activity

PMID:11445076[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Periplasm

PMID:9298647[6]

EchoLocation:sseA


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MRENLRYVIQ YHAHTIRILV RIVAQTAKSA SFACRFSLNI RQFSLTPAKM EMPMSTTWFV
GADWLAEHID DPEIQIIDAR MASPGQEDRN VAQEYLNGHI PGAVFFDIEA LSDHTSPLPH
MLPRPETFAV AMRELGVNQD KHLIVYDEGN LFSAPRAWWM LRTFGVEKVS ILGGGLAGWQ
RDDLLLEEGA VELPEGEFNA AFNPEAVVKV TDVLLASHEN TAQIIDARPA ARFNAEVDEP
RPGLRRGHIP GALNVPWTEL VREGELKTTD ELDAIFFGRG VSYDKPIIVS CGSGVTAAVV
LLALATLDVP NVKLYDGAWS EWGARADLPV EPVK
Length

334

Mol. Wt

37.002 kDa

pI

4.9 (calculated)

Extinction coefficient

52,940 - 53,190 (calc based on 6 Y, 8 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P31142

Domain

8..129

PF00581 Rhodanese-like domain

PMID:19920124[7]

Domain

157..272

PF00581 Rhodanese-like domain

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=sseA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111451

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946993

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008299

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P31142

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11600

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11600

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946993

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001548

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1557

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Colnaghi, R et al. (2001) Properties of the Escherichia coli rhodanese-like protein SseA: contribution of the active-site residue Ser240 to sulfur donor recognition. FEBS Lett. 500 153-6 PubMed
  6. Link, AJ et al. (1997) Identifying the major proteome components of Haemophilus influenzae type-strain NCTC 8143. Electrophoresis 18 1314-34 PubMed
  7. 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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