sdaB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

SdaB

Synonyms

L-serine deaminase II[1], B2797[2][1], SdaB[2][1], L-threonine deaminase II[2][1], L-serine deaminase 2[2][1], L-serine dehydratase 2[2][1], SDH-2[2][1], L-SD2[2][1], L-serine hydro-lyase 2 (deaminating)[2][1] , ECK2792, JW2768, b2797

Product description

LSERINEDEAM2[2][3]

L-Serine deaminase II; L-SD2[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004644

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.3.1.17

F

Seeded from EcoCyc (v14.0)

complete

GO:0005506

iron ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408

F

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004644

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0312

P

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0051536

iron-sulfur cluster binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0411

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

blc

PMID:16606699[5]

Experiment(s):EBI-1143989

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Cytoplasm

PMID:8385012[6], PMID:8436113[7]

EchoLocation:sdaB


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MISVFDIFKI GIGPSSSHTV GPMKAGKQFT DDLIARNLLK DVTRVVVDVY GSLSLTGKGH
HTDIAIIMGL AGNLPDTVDI DSIPSFIQDV NTHGRLMLAN GQHEVEFPVD QCMNFHADNL
SLHENGMRIT ALAGDKVVYS QTYYSIGGGF IVDEEHFGQQ DSAPVEVPYP YSSAADLQKH
CQETGLSLSG LMMKNELALH SKEELEQHLA NVWEVMRGGI ERGISTEGVL PGKLRVPRRA
AALRRMLVSQ DKTTTDPMAV VDWINMFALA VNEENAAGGR VVTAPTNGAC GIIPAVLAYY
DKFIREVNAN SLARYLLVAS AIGSLYKMNA SISGAEVGCQ GEVGVACSMA AAGLAELLGA
SPAQVCIAAE IAMEHNLGLT CDPVAGQVQV PCIERNAIAA VKAVNAARMA LRRTSEPRVC
LDKVIETMYE TGKDMNAKYR ETSRGGLAMK IVACD
Length

455

Mol. Wt

48.752 kDa

pI

5.7 (calculated)

Extinction coefficient

28,880 - 30,130 (calc based on 12 Y, 2 W, and 10 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

182..450

PF03313 Serine dehydratase alpha chain

PMID:19920124[8]

Domain

3..159

PF03315 Serine dehydratase beta chain

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=sdaB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130704

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947262

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009172

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P30744

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11623

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11623

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947262

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001571

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1580

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Shao, Z & Newman, EB (1993) Sequencing and characterization of the sdaB gene from Escherichia coli K-12. Eur. J. Biochem. 212 777-84 PubMed
  7. Su, H et al. (1993) Use of gene fusions of the structural gene sdaA to purify L-serine deaminase 1 from Escherichia coli K-12. Eur. J. Biochem. 211 521-7 PubMed
  8. 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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