rtcR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RtcR

Synonyms

sigma 54-dependent transcriptional regulator of rtcBA expression[1], B3422[2][1], YhgB[2][1], RtcR[2][1] , ECK3408, JW3385, yhgB, b3422

Product description

RtcR transcriptional regulator[2]; RtcR transcriptional activator[3]

Transcriptional regulator for rtcAB[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000160

two-component signal transduction system (phosphorelay)

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0902

P

Seeded from EcoCyc (v14.0)

complete

GO:0000166

nucleotide binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:9738023[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:9738023[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P07604
UniProtKB:P45512
UniProtKB:P38022
UniProtKB:P37930
UniProtKB:P28614
UniProtKB:P12627
UniProtKB:P12626
UniProtKB:P09133
UniProtKB:P06519
UniProtKB:P37344
UniProtKB:P10046
UniProtKB:P06184
UniProtKB:Q04849
UniProtKB:P0AFB8
UniProtKB:P26408
UniProtKB:P31908
UniProtKB:P23747
UniProtKB:Q00934
UniProtKB:Q06065
UniProtKB:P14375
UniProtKB:P19323

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002078

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002078

C

Seeded from EcoCyc (v14.0)

complete

GO:0008134

transcription factor binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002078

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:9738023[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:9738023[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P07604
UniProtKB:P45512
UniProtKB:P38022
UniProtKB:P37930
UniProtKB:P28614
UniProtKB:P12627
UniProtKB:P12626
UniProtKB:P09133
UniProtKB:P06519
UniProtKB:P37344
UniProtKB:P10046
UniProtKB:P06184
UniProtKB:Q04849
UniProtKB:P0AFB8
UniProtKB:P26408
UniProtKB:P31908
UniProtKB:P23747
UniProtKB:Q00934
UniProtKB:Q06065
UniProtKB:P14375
UniProtKB:P19323

F

Seeded from EcoCyc (v14.0)

complete

GO:0017111

nucleoside-triphosphatase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:9738023[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:9738023[5]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P07604
Swiss-Prot:P45512
Swiss-Prot:P38022
Swiss-Prot:P37930
Swiss-Prot:P28614
Swiss-Prot:P12627
Swiss-Prot:P12626
Swiss-Prot:P09133
Swiss-Prot:P06519
Swiss-Prot:P37344
Swiss-Prot:P10046
Swiss-Prot:P06184
Swiss-Prot:Q04849
Swiss-Prot:P0AFB8
Swiss-Prot:P26408
Swiss-Prot:P31908
Swiss-Prot:P23747
Swiss-Prot:Q00934
Swiss-Prot:Q06065
Swiss-Prot:P14375
Swiss-Prot:P19323

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dld

PMID:16606699[6]

Experiment(s):EBI-1145849

Protein

dnaK

PMID:16606699[6]

Experiment(s):EBI-1145849

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1145849

Protein

sdhA

PMID:16606699[6]

Experiment(s):EBI-1145849

Protein

rpsB

PMID:16606699[6]

Experiment(s):EBI-1145849

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MRKTVAFGFV GTVLDYAGRG SQRWSKWRPT LCLCQQESLV IDRLELLHDA RSRSLFETLK
RDIASVSPET EVVSVEIELH NPWDFEEVYA CLHDFARGYE FQPEKEDYLI HITTGTHVAQ
ICWFLLAEAR YLPARLIQSS PPRKKEQPRG PGEVTIIDLD LSRYNAIASR FAEERQQTLD
FLKSGIATRN PHFNRMIEQI EKVAIKSRAP ILLNGPTGAG KSFLARRILE LKQARHQFSG
AFVEVNCATL RGDTAMSTLF GHVKGAFTGA RESREGLLRS ANGGMLFLDE IGELGADEQA
MLLKAIEEKT FYPFGSDRQV SSDFQLIAGT VRDLRQLVAE GKFREDLYAR INLWTFTLPG
LRQRQEDIEP NLDYEVERHA SLTGDSVRFN TEARRAWLAF ATSPQATWRG NFRELSASVT
RMATFATSGR ITLDVVEDEI NRLRYNWQES RPSALTALLG AEAENIDLFD RMQLEHVIAI
CRQAKSLSAA GRQLFDVSRQ GKASVNDADR LRKYLARFGL TWEAVQDQHS SS
Length

532

Mol. Wt

60.3 kDa

pI

7.1 (calculated)

Extinction coefficient

65,890 - 66,640 (calc based on 11 Y, 9 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

186..357

PF00158 Sigma-54 interaction domain

PMID:19920124[7]

Domain

1..185

PF06956 Regulator of RNA terminal phosphate cyclase

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rtcR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131296

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947928

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011174

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P38035

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12356

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12356

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947928

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002224

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2259

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Genschik, P et al. (1998) Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon. J. Biol. Chem. 273 25516-26 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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