rsmC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RsmC

Synonyms

16S RNA m2G1207 methylase [1], B4371 [2][1], YjjT [2][1], RsmC [2][1] , ECK4362, JW4333, yjjT, b4371

Product description

16S rRNA m2G1207 methyltransferase[2][3]

16S rRNA m(2)G1207 methyltransferase, SAM-dependent[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0009451

RNA modification

P

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0000287

magnesium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0460

F

Seeded from EcoCyc (v14.0)

complete

GO:0003676

nucleic acid binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002052

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01862

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

PMID:9873033[5]

IC: Inferred by Curator

GO:0008990

C

Seeded from EcoCyc (v14.0)

complete

GO:0008990

rRNA (guanine-N2-)-methyltransferase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01862

F

Seeded from EcoCyc (v14.0)

complete

GO:0008990

rRNA (guanine-N2-)-methyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013675

F

Seeded from EcoCyc (v14.0)

complete

GO:0008990

rRNA (guanine-N2-)-methyltransferase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.1.1.52

F

Seeded from EcoCyc (v14.0)

complete

GO:0031167

rRNA methylation

PMID:9873033[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0070475

rRNA base methylation

PMID:17576679[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpsC

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

ycgE

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rplD

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rpsD

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

yciH

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rplB

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rpsI

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

udk

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rpsG

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

hyaB

PMID:16606699[7]

Experiment(s):EBI-1147905

Protein

rpsM

PMID:16606699[7]

Experiment(s):EBI-1147905
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARLDTA ASRAHTQQFH HWQVLSRQMG
DNARFSLVAT ADDVADCDTL IYYWPKNKPE AQFQLMNLLS LLPVGTDIFV VGENRSGVRS
AEQMLADYAP LNKVDSARRC GLYFGRLEKQ PVFDAEKFWG EYSVDGLTVK TLPGVFSRDG
LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SVAFARHSPK IRLTLCDVSA PAVEASRATL
AANGVEGEVF ASNVFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR
IVANAFLPYP DVLDETFGFH EVIAQTGRFK VYRAIMTRQA KKG
Length

343

Mol. Wt

37.624 kDa

pI

6.4 (calculated)

Extinction coefficient

26,930 - 27,430 (calc based on 7 Y, 3 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P39406

Domain

166..333

PF05175 Methyltransferase small domain

PMID:19920124[8]

Domain

8..162

PF08468 Methyltransferase small domain N-terminal

PMID:19920124[8]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rsmC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16132189

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948892

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0014336

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P39406

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7950

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12596

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948892

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004443

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2481

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Tscherne, JS et al. (1999) Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli. J. Biol. Chem. 274 924-9 PubMed
  6. ↑ Sunita, S et al. (2007) Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC. Nucleic Acids Res. 35 4264-74 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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