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References Suggestions


Standard Name


Gene Synonym(s)

ECK2570, b2572, JW2556, mclA, yfiJ[1], yfiJ

Product Desc.

anti-sigma factor that inhibits sigmaE[2]; anti-sigma factor[3]

Anti-RpoE sigma factor, spans inner membrane[4]

Product Synonyms(s)

anti-sigma factor[1], B2572[2][1], YfiJ[2][1], MclA[2][1], RseA[2][1] , ECK2570, JW2556, mclA, yfiJ, b2572

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): rpoE-rseABC[2], rseABC[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The anti-sigma N-terminal RseA domain is linked to the periplasmic domain by a single membrane domain spanning residues 100-118. The periplasmic domain is first degraded by DegS. Subsequent cytoplasmic domain degradation requires YaeL. RseA Tyr-46 is phoshorylated. de-phosphorylated by Etp. rseA is transiently induced after a cold shock, dependent on the presence of PNPase. Mutants have elevated OM vesiculation (McBroom, 2006).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.