rluC:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
RluC |
|---|---|
| Synonyms |
23S rRNA pseudouridylate synthase[1], B1086[2][1], YceC[2][1], RluC[2][1] , ECK1071, JW1072, yceC, b1086 |
| Product description |
23S rRNA pseudouridine synthase[2][3] 23S rRNA pseudouridine synthase; specific to U955, U2504, and U2580; non-essential gene[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009982 |
pseudouridine synthase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009982 |
pseudouridine synthase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0000455 |
enzyme-directed rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0009982 |
pseudouridine synthase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009982 |
pseudouridine synthase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0031118 |
rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0031118 |
rRNA pseudouridine synthesis |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
accA |
Experiment(s):EBI-882671 | ||
|
Protein |
aceE |
Experiment(s):EBI-882671 | ||
|
Protein |
aceF |
Experiment(s):EBI-882671 | ||
|
Protein |
aidB |
Experiment(s):EBI-882671 | ||
|
Protein |
yncE |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
deaD |
Experiment(s):EBI-882671 | ||
|
Protein |
hrpA |
Experiment(s):EBI-882671 | ||
|
Protein |
lpdA |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
pssA |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rhlE |
Experiment(s):EBI-882671 | ||
|
Protein |
rplA |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplB |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplC |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplD |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplE |
Experiment(s):EBI-882671 | ||
|
Protein |
rplF |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplI |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplM |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplO |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplS |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplV |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rplX |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rpmB |
Experiment(s):EBI-882671 | ||
|
Protein |
rpoB |
Experiment(s):EBI-882671 | ||
|
Protein |
rpoC |
Experiment(s):EBI-882671 | ||
|
Protein |
rpsA |
Experiment(s):EBI-882671 | ||
|
Protein |
rpsB |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rpsC |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rpsD |
Experiment(s):EBI-882671 | ||
|
Protein |
rpsE |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rpsG |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rpsM |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
secA |
Experiment(s):EBI-882671 | ||
|
Protein |
spoT |
Experiment(s):EBI-882671 | ||
|
Protein |
srmB |
Experiment(s):EBI-882671 | ||
|
Protein |
rnr |
Experiment(s):EBI-882671, EBI-883997, EBI-890236 | ||
|
Protein |
ybjD |
Experiment(s):EBI-882671 | ||
|
Protein |
ycbY |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
rluB |
Experiment(s):EBI-882671, EBI-890236 | ||
|
Protein |
yfiF |
Experiment(s):EBI-882671, EBI-879491, EBI-890236 | ||
|
Protein |
ygiF |
Experiment(s):EBI-882671 | ||
|
Protein |
yhiR |
Experiment(s):EBI-882671 | ||
|
Protein |
hupA |
Experiment(s):EBI-890236 | ||
|
Protein |
hupB |
Experiment(s):EBI-890236 | ||
|
Protein |
rplL |
Experiment(s):EBI-890236 | ||
|
Protein |
rplN |
Experiment(s):EBI-890236 | ||
|
Protein |
rplP |
Experiment(s):EBI-890236 | ||
|
Protein |
rplQ |
Experiment(s):EBI-890236 | ||
|
Protein |
rplR |
Experiment(s):EBI-890236 | ||
|
Protein |
rplT |
Experiment(s):EBI-890236 | ||
|
Protein |
rplU |
Experiment(s):EBI-890236 | ||
|
Protein |
rpsF |
Experiment(s):EBI-890236 | ||
|
Protein |
rpsN |
Experiment(s):EBI-890236 | ||
|
Protein |
rpsP |
Experiment(s):EBI-890236 | ||
|
Protein |
rpsR |
Experiment(s):EBI-890236 | ||
|
Protein |
rpsT |
Experiment(s):EBI-890236 | ||
|
Protein |
yibL |
Experiment(s):EBI-890236 | ||
|
Protein |
rluE |
Experiment(s):EBI-890236 | ||
|
Protein |
rplB |
Experiment(s):EBI-1138798 | ||
|
Protein |
rpoB |
Experiment(s):EBI-1138798 | ||
|
Protein |
rplA |
Experiment(s):EBI-1138798 | ||
|
Protein |
uspG |
Experiment(s):EBI-1138798 | ||
|
Protein |
rplU |
Experiment(s):EBI-1138798 | ||
|
Protein |
rpsM |
Experiment(s):EBI-1138798 | ||
|
Protein |
rpsG |
Experiment(s):EBI-1138798 | ||
|
Protein |
rpoC |
Experiment(s):EBI-1138798 | ||
|
Protein |
yedD |
Experiment(s):EBI-1138798 | ||
|
Protein |
ptsP |
Experiment(s):EBI-1138798 | ||
|
Protein |
rplQ |
Experiment(s):EBI-1138798 | ||
|
Protein |
secA |
MALDI(Z-score):24.385638 | ||
|
Protein |
rplP |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplE |
LCMS(ID Probability):81.2 MALDI(Z-score):30.574216 | ||
|
Protein |
hupB |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsM |
LCMS(ID Probability):99.6 MALDI(Z-score):17.503927 | ||
|
Protein |
rplO |
LCMS(ID Probability):99.6 MALDI(Z-score):30.739506 | ||
|
Protein |
rplN |
LCMS(ID Probability):99.6 MALDI(Z-score):2.281625 | ||
|
Protein |
rpmB |
LCMS(ID Probability):97.9 MALDI(Z-score):17.053160 | ||
|
Protein |
rplI |
LCMS(ID Probability):99.6 MALDI(Z-score):37.856150 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsR |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplT |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplU |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.6 MALDI(Z-score):19.395974 | ||
|
Protein |
hupA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsA |
LCMS(ID Probability):98.1 MALDI(Z-score):28.357209 | ||
|
Protein |
rplX |
LCMS(ID Probability):99.6 MALDI(Z-score):21.448910 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplM |
LCMS(ID Probability):99.6 MALDI(Z-score):30.778814 | ||
|
Protein |
rpsD |
LCMS(ID Probability):80.8 MALDI(Z-score):35.042694 | ||
|
Protein |
rplB |
LCMS(ID Probability):99.6 MALDI(Z-score):38.200016 | ||
|
Protein |
rplQ |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsC |
LCMS(ID Probability):99.6 MALDI(Z-score):26.431199 | ||
|
Protein |
rplF |
LCMS(ID Probability):99.6 MALDI(Z-score):37.043758 | ||
|
Protein |
rplA |
LCMS(ID Probability):99.6 MALDI(Z-score):31.232887 | ||
|
Protein |
rplR |
LCMS(ID Probability):99.6 | ||
|
Protein |
srmB |
MALDI(Z-score):25.011900 | ||
|
Protein |
rplD |
LCMS(ID Probability):99.6 MALDI(Z-score):23.361680 | ||
|
Protein |
aidB |
MALDI(Z-score):28.068367 | ||
|
Protein |
ygiF |
MALDI(Z-score):38.667044 | ||
|
Protein |
rlmL |
LCMS(ID Probability):99.6 MALDI(Z-score):27.193001 | ||
|
Protein |
pssA |
LCMS(ID Probability):99.0 MALDI(Z-score):28.761839 | ||
|
Protein |
hrpA |
MALDI(Z-score):18.919885 | ||
|
Protein |
spoT |
MALDI(Z-score):23.376874 | ||
|
Protein |
rnr |
LCMS(ID Probability):99.6 MALDI(Z-score):32.605279 | ||
|
Protein |
yhiR |
MALDI(Z-score):39.672540 | ||
|
Protein |
ybcJ |
LCMS(ID Probability):99.6 MALDI(Z-score):24.933504 | ||
|
Protein |
yibL |
LCMS(ID Probability):99.6 MALDI(Z-score):3.839710 | ||
|
Protein |
yfiF |
LCMS(ID Probability):99.6 MALDI(Z-score):39.923321 | ||
|
Protein |
yncE |
LCMS(ID Probability):99.6 MALDI(Z-score):35.663691 | ||
|
Protein |
ybjD |
MALDI(Z-score):19.204851 | ||
|
Protein |
rluE |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplL |
LCMS(ID Probability):99.6 | ||
| edit table |
</protect>
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
cytoplasm |
From EcoCyc[3] |
| ||
| edit table |
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Notes
Structure and Physical Properties
<protect>
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MKTETPSVKI VAITADEAGQ RIDNFLRTQL KGVPKSMIYR ILRKGEVRVN KKRIKPEYKL EAGDEVRIPP VRVAEREEEA VSPHLQKVAA LADVILYEDD HILVLNKPSG TAVHGGSGLS FGVIEGLRAL RPEARFLELV HRLDRDTSGV LLVAKKRSAL RSLHEQLREK GMQKDYLALV RGQWQSHVKS VQAPLLKNIL QSGERIVRVS QEGKPSETRF KVEERYAFAT LVRCSPVTGR THQIRVHTQY AGHPIAFDDR YGDREFDRQL TEAGTGLNRL FLHAAALKFT HPGTGEVMRI EAPMDEGLKR CLQKLRNAR |
| Length |
319 |
| Mol. Wt |
36.026 kDa |
| pI |
10.2 (calculated) |
| Extinction coefficient |
15,930 - 16,180 (calc based on 7 Y, 1 W, and 2 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 Huang, L et al. (1998) Identification of two Escherichia coli pseudouridine synthases that show multisite specificity for 23S RNA. Biochemistry 37 15951-7 PubMed
- ↑ Conrad, J et al. (1998) The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA. J. Biol. Chem. 273 18562-6 PubMed
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 7.27 7.28 7.29 7.30 7.31 7.32 7.33 7.34 7.35 7.36 7.37 7.38 7.39 7.40 7.41 7.42 7.43 7.44 7.45 7.46 7.47 7.48 7.49 7.50 7.51 7.52 7.53 7.54 7.55 7.56 7.57 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 9.18 9.19 9.20 9.21 9.22 9.23 9.24 9.25 9.26 9.27 9.28 9.29 9.30 9.31 9.32 9.33 9.34 9.35 9.36 9.37 9.38 9.39 9.40 9.41 9.42 9.43 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ 10.0 10.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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