rlmC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RlmC

Synonyms

23S rRNA (uracil-5)-methyltransferase[1], B2785[2][1], YgcA[2][1], RumA[2][1] , ECK2779, JW2756, ygcA, b2785

Product description

23S ribosomal RNA 5-methyluridine methyltransferase[2][3]

23S rRNA (uracil-5)-methyltransferase, responsible for modification at position U1939, SAM-dependent[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MAQFYSAKRR TTTRQIITVS VNDLDSFGQG VARHNGKTLF IPGLLPQENA EVTVTEDKKQ
YARAKVVRRL SDSPERETPR CPHFGVCGGC QQQHASVDLQ QRSKSAALAR LMKHDVSEVI
ADVPWGYRRR ARLSLNYLPK TQQLQMGFRK AGSSDIVDVK QCPILAPQLE ALLPKVRACL
GSLQAMRHLG HVELVQATSG TLMILRHTAP LSSADREKLE RFSHSEGLDL YLAPDSEILE
TVSGEMPWYD SNGLRLTFSP RDFIQVNAGV NQKMVARALE WLDVQPEDRV LDLFCGMGNF
TLPLATQAAS VVGVEGVPAL VEKGQQNARL NGLQNVTFYH ENLEEDVTKQ PWAKNGFDKV
LLDPARAGAA GVMQQIIKLE PIRIVYVSCN PATLARDSEA LLKAGYTIAR LAMLDMFPHT
GHLESMVLFS RVK
Length

433

Mol. Wt

48.051 kDa

pI

8.7 (calculated)

Extinction coefficient

35,410 - 36,285 (calc based on 9 Y, 4 W, and 7 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P55135

Domain

10..67

PF01938 TRAM domain

PMID:19920124[5]

Domain

95..432

PF05958 tRNA (Uracil-5-)-methyltransferase

PMID:19920124[5]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rumA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130692

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947243

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002924

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P55135

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6449

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13427

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947243

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003049

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3201

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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