rffA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RffA

Synonyms

TDP-4-oxo-6-deoxy-D-glucose transaminase[1], B3791[2][1], Rff[2][1], YifI[2][1], RffA[2][1], FcnA[2][1], WecE[2][1] , ECK3783, JW3765, rff, wecE, yifI, b3791

Product description

Lipid III biosynthesis; needed for ECA synthesis[3]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015421

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015422

F

Seeded from EcoCyc (v14.0)

complete

GO:0009103

lipopolysaccharide biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0448

P

Seeded from EcoCyc (v14.0)

complete

GO:0030170

pyridoxal phosphate binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015421

F

Seeded from EcoCyc (v14.0)

complete

GO:0030170

pyridoxal phosphate binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015422

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

moaC

PMID:16606699[4]

Experiment(s):EBI-1146684

Protein

yghZ

PMID:16606699[4]

Experiment(s):EBI-1146684

Protein

groL

PMID:16606699[4]

Experiment(s):EBI-1146684

Protein

rplB

PMID:16606699[4]

Experiment(s):EBI-1146684
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MIPFNAPPVV GTELDYMQSA MGSGKLCGDG GFTRRCQQWL EQRFGSAKVL LTPSCTASLE
MAALLLDIQP GDEVIMPSYT FVSTANAFVL RGAKIVFVDV RPDTMNIDET LIEAAITDKT
RVIVPVHYAG VACEMDTIMA LAKKHNLFVV EDAAQGVMST YKGRALGTIG HIGCFSFHET
KNYTAGGEGG ATLINDKALI ERAEIIREKG TNRSQFFRGQ VDKYTWRDIG SSYLMSDLQA
AYLWAQLEAA DRINQQRLAL WQNYYDALAP LAKAGRIELP SIPDGCVQNA HMFYIKLRDI
DDRSALINFL KEAEIMAVFH YIPLHGCPAG EHFGEFHGED RYTTKESERL LRLPLFYNLS
PVNQRTVIAT LLNYFS
Length

376

Mol. Wt

41.901 kDa

pI

6.1 (calculated)

Extinction coefficient

44,350 - 45,225 (calc based on 15 Y, 4 W, and 7 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

9..372

PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family

PMID:19920124[5]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rffA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131647

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948296

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012384

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P27833

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11456

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11456

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948296

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001419

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1425

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  5. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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