rfbC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RfbC

Synonyms

dTDP-4-deoxyrhamnose-3,5-epimerase[1], B2038[2][1], RfbC[2][1], RmlC[2][1] , ECK2032, JW2023, rfbD, rmlC, b2038

Product description

DTDPDEHYDRHAMEPIM[2][3];

Component of dTDP-L-rhamnose synthetase[2][3]

dTDP-4-deoxyrhamnose-3,5-epimerase[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0008830

dTDP-4-dehydrorhamnose 3,5-epimerase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000888

F

Seeded from EcoCyc (v14.0)

complete

GO:0008830

dTDP-4-dehydrorhamnose 3,5-epimerase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:5.1.3.13

F

Seeded from EcoCyc (v14.0)

complete

GO:0009103

lipopolysaccharide biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000888

P

Seeded from EcoCyc (v14.0)

complete

GO:0019305

dTDP-rhamnose biosynthetic process

P

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0009103

lipopolysaccharide biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0448

P

Seeded from EcoCyc (v14.0)

complete

GO:0016853

isomerase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0413

F

Seeded from EcoCyc (v14.0)

complete

GO:0042803

protein homodimerization activity

F

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of dTDP-L-rhamnose synthetase

could be indirect

Protein

groL

PMID:15690043[5]

Experiment(s):EBI-887248

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1141698

Protein

yhbT

PMID:16606699[6]

Experiment(s):EBI-1141698

Protein

yhjA

PMID:16606699[6]

Experiment(s):EBI-1141698

Protein

groL

PMID:19402753[7]

MALDI(Z-score):17.053160

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNVIRTEIED VLILEPRVFG DDRGFFYESF NQSAFEHILG YPVSFVQDNH SRSSKNVLRG
LHFQRGEYAQ DKLVRCTHGA VFDVAVDIRP NSVSFGKWVG VLLSADNKQQ LWIPKGFAHG
FLVLSDIAEF QYKTTNYYHP ESDCGICWND ERIAIDWPQT SGLILSPKDE RLFTLDELIR
LKLIA
Length

185

Mol. Wt

21.27 kDa

pI

5.7 (calculated)

Extinction coefficient

30,940 - 31,315 (calc based on 6 Y, 4 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

3..178

PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rfbC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129978

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947482

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006759

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P37745

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11979

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11979

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947482

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001904

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1922

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. 6.0 6.1 6.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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