recA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
recA |
|---|---|
| Gene Synonym(s) |
ECK2694, b2699, JW2669, lexB, srf, umuB, zab, recH, rnmB, tif, umuR[1], umuR |
| Product Desc. |
DNA strand exchange and renaturation, DNA-dependent ATPase, DNA- and ATP-dependent coprotease[2]; DNA strand exchange and recombination protein with protease and nuclease activity[3] General recombination and DNA repair; pairing and strand exchange; role in cleavage of LexA repressor, SOS mutagenesis[4] |
| Product Synonyms(s) |
B2699[2][1], Tif[2][1], UmuB[2][1], Zab[2][1], Srf[2][1], RnmB[2][1], RecH[2][1], LexB[2][1], RecA[2][1] , ECK2694, JW2669, lexB, recH, rnmB, srf, tif, umuB, umuR, zab, b2699 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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Notes
RecA does not bind to DNA with extensive stem-loop structures, except in the presence of SSB. RecA is required for polV lesion bypass. RecA filamentation is inhibited by RecX. Binds TrxA (Kumar, 2004).[4]
RecA lacking mutants exhibited the same frequency as the wild type when exposed to sublethal concentrations of the antibiotics Ampicillin, Ceftazidime, Imipenem, Fosfomycin, Ciprofloxacin, Trimethoprim, and Sulfamethoxazole.(PMID:21212055)
RecA lacking mutants exhibited different frequencies then the wild type when exposed to sublethal concentrations of the antibiotics Gentamicin, Rifampicin, Chloramphenicol (PMID:21212055)
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
