ravA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YieN

Synonyms

fused predicted transcriptional regulator: sigma54 activator protein[1], conserved protein[1], B3746[2][1], YieN[2][1], RavA[2][1] , ECK3740, JW3725, yieN, b3746

Product description

regulatory ATPase[2][3];

Component of regulatory ATPase[3]

Hexameric AAA+ family ATPase, funtion unknown; ATPase stimulated by binding to CadA decamers[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011704

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01625

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0016787

hydrolase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc (v14.0)

complete

GO:0016887

ATPase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01625

F

Seeded from EcoCyc (v14.0)

complete

GO:0016887

ATPase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011704

F

Seeded from EcoCyc (v14.0)

complete

GO:0017111

nucleoside-triphosphatase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of regulatory ATPase

could be indirect

Protein

accA

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

intQ

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

cadA

PMID:15690043[5]

Experiment(s):EBI-881046, EBI-881973

Protein

dnaK

PMID:15690043[5]

Experiment(s):EBI-881046, EBI-881973

Protein

frdA

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

fucU

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

ldcC

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

rplJ

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-881046

Protein

accB

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

accC

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

ggt

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

grpE

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

infB

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

lpdA

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

rpsP

PMID:15690043[5]

Experiment(s):EBI-881973

Protein

ompA

PMID:19402753[6]

MALDI(Z-score):30.913247

Protein

grpE

PMID:19402753[6]

LCMS(ID Probability):99.0

Protein

ompC

PMID:19402753[6]

MALDI(Z-score):29.242507

Protein

cadA

PMID:19402753[6]

LCMS(ID Probability):99.6 MALDI(Z-score):28.387013

Protein

tdcE

PMID:19402753[6]

LCMS(ID Probability):99.4

Protein

ggt

PMID:19402753[6]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MTKGRHFIMA HPHLLAERIS RLSSSLEKGL YERSHAIRLC LLAALSGESV FLLGPPGIAK
SLIARRLKFA FQNARAFEYL MTRFSTPEEV FGPLSIQALK DEGRYERLTS GYLPEAEIVF
LDEIWKAGPA ILNTLLTAIN ERQFRNGAHV EKIPMRLLVA ASNELPEADS SLEALYDRML
IRLWLDKVQD KANFRSMLTS QQDENDNPVP DALQVTDEEY ERWQKEIGEI TLPDHVFELI
FMLRQQLDKL PDAPYVSDRR WKKAIRLLQA SAFFSGRSAV APVDLILLKD CLWYDAQSLN
LIQQQIDVLM TGHAWQQQGM LTRLGAIVQR HLQLQQQQSD KTALTVIRLG GIFSRRQQYQ
LPVNVTASTL TLLLQKPLKL HDMEVVHISF ERSALEQWLS KGGEIRGKLN GIGFAQKLNL
EVDSAQHLVV RDVSLQGSTL ALPGSSAEGL PGEIKQQLEE LESDWRKQHA LFSEQQKCLF
IPGDWLGRIE ASLQDVGAQI RQAQQC
Length

506

Mol. Wt

57.361 kDa

pI

6.8 (calculated)

Extinction coefficient

62,910 - 63,410 (calc based on 9 Y, 9 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

41..171

PF07728 AAA domain (dynein-related subfamily)

PMID:19920124[7]

Domain

442..498

PF12592 Protein of unknown function (DUF3763)

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ravA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111646

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948256

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012247

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P31473

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11731

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11731

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948256

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001670

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1682

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. ↑ 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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