pspC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PspC

Synonyms

DNA-binding transcriptional activator[1], B1306[2][1], PspC[2][1], phage shock protein[2][1] , ECK1301, JW1299, b1306

Product description

PspC transcriptional regulator; toxin of a PspC-PspB toxin-antitoxin pair[2][3];

Component of PspC transcriptional regulator; toxin of a PspC-PspB toxin-antitoxin pair[3]

Positive regulatory gene, cooperatively with PspB; facilitates binding of PspA to PspB; membrane protein; dimer[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006950

response to stress

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0346

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of PspC transcriptional regulator; toxin of a PspC-PspB toxin-antitoxin pair

could be indirect

Protein

pspC

SDS-resistant homodimers

PMID:12562786[5]


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAGINLNKKL WRIPQQGMVR GVCAGIANYF DVPVKLVRIL VVLSIFFGLA LFTLVAYIIL
SFALDPMPDN MAFGEQLPSS SELLDEVDRE LAASETRLRE MERYVTSDTF TLRSRFRQL
Length

119

Mol. Wt

13.516 kDa

pI

6.8 (calculated)

Extinction coefficient

9,970 - 10,095 (calc based on 3 Y, 1 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

7..69

PF04024 PspC domain

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=pspC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129267

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945499

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004391

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AFN2

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10778

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10778

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945499

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000769

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0771

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Adams, H et al. (2003) Interactions between phage-shock proteins in Escherichia coli. J. Bacteriol. 185 1174-80 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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