paaX:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PaaX

Synonyms

DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive[1], B1399[2][1], YdbY[2][1], PaaX[2][1] , ECK1396, JW1394, ydbY, b1399

Product description

PaaX transcriptional regulator[2]; PaaX transcriptional repressor[3]

Phenylacetic acid degradation[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

aceF

PMID:15690043[5]

Experiment(s):EBI-878671

Protein

lpdA

PMID:15690043[5]

Experiment(s):EBI-878671, EBI-881427

Protein

rplB

PMID:16606699[6]

Experiment(s):EBI-1139767

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1139767

Protein

rpmB

PMID:16606699[6]

Experiment(s):EBI-1139767

Protein

rplC

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rplO

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rplT

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rplU

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rpmB

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rpsL

PMID:15690043[5]

Experiment(s):EBI-881427

Protein

rpmB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsL

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplM

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplO

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplT

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSKLDTFIQH AVNAVPVSGT SLISSLYGDS LSHRGGEIWL GSLAALLEGL GFGERFVRTA
LFRLNKEGWL DVSRIGRRSF YSLSDKGLRL TRRAESKIYR AEQPAWDGKW LLLLSEGLDK
STLADVKKQL IWQGFGALAP SLMASPSQKL ADVQTLLHEA GVADNVICFE AQIPLALSRA
ALRARVEECW HLTEQNAMYE TFIQSFRPLV PLLKEAADEL TPERAFHIQL LLIHFYRRVV
LKDPLLPEEL LPAHWAGHTA RQLCINIYQR VAPAALAFVS EKGETSVGEL PAPGSLYFQR
FGGLNIEQEA LCQFIR
Length

316

Mol. Wt

35.295 kDa

pI

7.6 (calculated)

Extinction coefficient

48,930 - 49,430 (calc based on 7 Y, 7 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

18..87

PF07848 PaaX-like protein

PMID:19920124[8]

Domain

103..282

PF08223 PaaX-like protein C-terminal domain

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=paaX taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129360

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945966

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004674

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76086

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6720

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13746

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945966

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003314

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3509

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. 6.0 6.1 6.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 7.2 7.3 7.4 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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