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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions


Standard Name


Gene Synonym(s)

ECK3239, b3251, JW3220, envB, mon, rodY, mreB_1[1][2]

Product Desc.


Component of longitudinal peptidoglycan synthesis/chromosome segregation-directing complex[3]

MreB filaments participate in directional chromosome movement and segregation; mecillinam resistance; forms membrane-associated coiled arrays; actin homolog; morphology[4]

Product Synonyms(s)

cell wall structural complex MreBCD, actin-like component MreB[1], B3251[2][1], RodY[2][1], Mon[2][1], EnvB[2][1], MreB_1[2][1], MreB[2][1] , ECK3239, envB, JW3220, mon, rodY, b3251

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mreBCD-yhdE-rng[2]

Quick Links

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Overexpression causes abnormal biofilm architecture, reduces motility and inhibits cell division. In operon with mreCD and the gene products form an essential membrane-bound complex responsible for cell morphology. Binds TrxA (Kumar, 2004).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.