mdtO:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YjcQ

Synonyms

predicted multidrug efflux system component[1], B4081[2][1], MdtO[2][1], YjcQ[2][1] , ECK4074, JW4042, sdsQ, yjcQ, b4081

Product description

predicted multidrug efflux system component[2][3]

PET family membrane translocase (MDR) of tripartite MdtNOP efflux pump; mdtP mutants are sensitive to acriflavin and puromycin[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MTFEIPFVAL SLAVLFYGIQ SNAFYTKFVA ILFVVATVLE IGSLFLIYKW SYGEPLIRLI
IAGPILMGCM FLMRTHRLGL VFFAVAIVAI YGQTFPAMLD YPEVVVRLTL WCIVVGLYPT
LLMTLIGVLW FPSRAISQMH QALNDRLDDA ISHLTDSLAP LPETRIEREA LALQKLNVFC
LADDANWRTQ NAWWQSCVAT VTYIYSTLNR YDPTSFADSQ AIIEFRQKLA SEINKLQHAV
AEGQCWQSDW RISESEAMAA RECNLENICQ TLLQLGQMDP NTPPTPAAKP PSMAADAFTN
PDYMRYAVKT LLACLICYTF YSGVDWEGIH TCMLTCVIVA NPNVGSSYQK MVLRFGGAFC
GAILALLFTL LVMPWLDNIV ELLFVLAPIF LLGAWIATSS ERSSYIGTQM VVTFALATLE
NVFGPVYDLV EIRDRALGII IGTVVSAVIY TFVWPESEAR TLPQKLAGTL GMLSKVMRIP
RQQEVTALRT YLQIRIGLHA AFNACEEMCQ RVALERQLDS EERALLIERS QTVIRQGRDL
LHAWDATWNS AQALDNALQP DRAGQFADAL EKYAAGLATA LSRSPQITLE ETPASQAILP
TLLKQEQHVC QLFARLPDWT APALTPATEQ AQGATQ
Length

636

Mol. Wt

70.87 kDa

pI

5.1 (calculated)

Extinction coefficient

112,300 - 114,175 (calc based on 20 Y, 15 W, and 15 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

30..561

PF04632 Fusaric acid resistance protein family

PMID:19920124[5]

<motif_map/>

tmhmm.php?gene=mdtO&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mdtO taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111683

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948582

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P32715

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948582

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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