kilR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

KilR

Synonyms

Rac prophage; inhibitor of ftsZ, killing protein[1], B1352[2][1], YdaD[2][1], Kil[2][1], KilR[3][1] , ECK1350, JW1347, kil, ydaD, b1352

Product description

Kil; Rac prophage killing protein[2]; Rac prophage; inhibitor of FtsZ, killing protein[3]

Killing function of the Rac prophage during zygotic induction; causes cell division arrest and altered cell morphology , suppressed by ftsZ overexpression[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007049

cell cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded from EcoCyc (v14.0)

complete

GO:0051301

cell division

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0132

P

Seeded from EcoCyc (v14.0)

complete

GO:0051782

negative regulation of cell division

PMID:8752325[5]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

GO:0051782

negative regulation of cell division

PMID:8752325[5]

IMP: Inferred from Mutant Phenotype

P

Induction of kilR expression causes filamentation. This effect is relieved by overexpression of FtsZ.

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MEIIMIAHHF GTDEIPRQCV TPGDYVLHEG RTYIASANNI KKRKLYIRNL TTKTFITDRM
IKVFLGRDGL PVKAESW
Length

77

Mol. Wt

8.92 kDa

pI

9.9 (calculated)

Extinction coefficient

9,970 - 10,095 (calc based on 3 Y, 1 W, and 1 C residues)


Domains/Motifs/Modification Sites

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Type Residues Description Notes References

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Structure
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Structures

<beststructure> gene=kilR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111255

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945921

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004537

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P38393

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12155

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12155

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945921

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002054

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2075

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Conter, A et al. (1996) Identification of a new inhibitor of essential division gene ftsZ as the kil gene of defective prophage Rac. J. Bacteriol. 178 5100-4 PubMed

Categories

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