kefA:Quickview

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Standard Name

kefA

Gene Synonym(s)

ECK0459, b0465, JW0454, aefA, mscK[1], mscK, pnuH

Product Desc.

KefA[2][3]

Mechanosensitive channel protein, intermediate conductance; regulation of ion balance and turgor pressure at high osmolarity; also may affect activity of mechanosensitive channel MscS[4]

Product Synonyms(s)

fused conserved protein[1], mechanosensitive channel protein[1], B0465[2][1], MscK[2][1], KefA[2][1], AefA[2][1] , aefA, ECK0459, JW0454, mscK, pnuH, b0465

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): kefA[2]

Regulation/Activity
Quick Links

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Notes

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Consistently co-purifies with the degradosome. Probable false positive lipoprotein prediction, 12 CM TMs, Cys not conserved. First 33 aa are predicted to be a type I signal peptide; the first 40 aa enable export of a fusion protein into the periplasm (McLaggan, 2002). mscS, kefA, yjeP, ybiO, ybdG and ynaI are paralogs.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.