kdsC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

KdsC

Synonyms

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase[1], B3198[2][1], YrbJ[2][1], KdsC[2][1], YrbI[2][1] , ECK3187, JW3165, yrbI, yrbJ, b3198

Product description

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase[2][3];

Component of [[:Category:Complex:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase|3-deoxy-D-manno-octulosonate 8-phosphate phosphatase]][2][3]

3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; KDO 8-P phosphatase; LPS biosynthesis; HAD22[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0030288

outer membrane-bounded periplasmic space

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0000287

magnesium ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0460

F

Seeded from EcoCyc (v14.0)

complete

GO:0019143

3-deoxy-manno-octulosonate-8-phosphatase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010023

F

Seeded from EcoCyc (v14.0)

complete

GO:0019143

3-deoxy-manno-octulosonate-8-phosphatase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.3.45

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of [[:Category:Complex:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase|3-deoxy-D-manno-octulosonate 8-phosphate phosphatase]]

could be indirect

Protein

plsB

PMID:16606699[5]

Experiment(s):EBI-1145130

Protein

sapF

PMID:16606699[5]

Experiment(s):EBI-1145130

Protein

rplM

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplP

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

slyD

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

ycgF

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rfaD

PMID:19402753[6]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Cytoplasm

PMID:12639950[7]

EchoLocation:kdsC


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSKAGASLAT CYGPVSADVI AKAENIRLLI LDVDGVLSDG LIYMGNNGEE LKAFNVRDGY
GIRCALTSDI EVAIITGRKA KLVEDRCATL GITHLYQGQS NKLIAFSDLL EKLAIAPENV
AYVGDDLIDW PVMEKVGLSV AVADAHPLLI PRADYVTRIA GGRGAVREVC DLLLLAQGKL
DEAKGQSI
Length

188

Mol. Wt

19.997 kDa

pI

5.0 (calculated)

Extinction coefficient

14,440 - 14,940 (calc based on 6 Y, 1 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

88..167

PF08282 haloacid dehalogenase-like hydrolase

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=kdsC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131088

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947717

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010506

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABZ4

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7663

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12804

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947717

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004211

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2656

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 6.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. Wu, J & Woodard, RW (2003) Escherichia coli YrbI is 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. J. Biol. Chem. 278 18117-23 PubMed
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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