iclR:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

IclR

Synonyms

DNA-binding transcriptional repressor[1], B4018[2][1], IclR[2][1], acetate operon repressor[2][1] , ECK4010, JW3978, b4018

Product description

IclR transcriptional repressor[2][3]

Repressor of aceBA operon[4]

EC number (for enzymes)


edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005471

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0006097

glyoxylate cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0329

P

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005471

P

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

hldD

PMID:15690043[5]

Experiment(s):EBI-885803

Protein

rpsC

PMID:16606699[6]

Experiment(s):EBI-1147301

Protein

aceF

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplA

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplT

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplU

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rplX

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsE

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsF

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsH

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsM

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsN

PMID:15690043[5]

Experiment(s):EBI-892341

Protein

rpsF

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplT

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsH

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplX

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplM

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsM

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rfaD

PMID:19402753[7]

MALDI(Z-score):21.217150

Protein

fadR

when fadR and iclR are acting together, they cause full repression of the ace operon

PMID:7033207[8]


edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MKMISTIQKK ETVMVAPIPA KRGRKPAVAT APATGQVQSL TRGLKLLEWI AESNGSVALT
ELAQQAGLPN STTHRLLTTM QQQGFVRQVG ELGHWAIGAH AFMVGSSFLQ SRNLLAIVHP
ILRNLMEESG ETVNMAVLDQ SDHEAIIIDQ VQCTHLMRMS APIGGKLPMH ASGAGKAFLA
QLSEEQVTKL LHRKGLHAYT HATLVSPVHL KEDLAQTRKR GYSFDDEEHA LGLRCLAACI
FDEHREPFAA ISISGPISRI TDDRVTEFGA MVIKAAKEVT LAYGGMR
Length

287

Mol. Wt

31.257 kDa

pI

8.8 (calculated)

Extinction coefficient

15,470 - 15,845 (calc based on 3 Y, 2 W, and 3 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

143..269

PF01614 Bacterial transcriptional regulator

PMID:19920124[9]

Domain

26..77

PF09339 IclR helix-turn-helix domain

PMID:19920124[9]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=iclR taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111675

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948524

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013136

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P16528

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10491

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10491

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948524

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000484

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0486

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Maloy, SR & Nunn, WD (1982) Genetic regulation of the glyoxylate shunt in Escherichia coli K-12. J. Bacteriol. 149 173-80 PubMed
  9. ↑ 9.0 9.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=iclR:Gene_Product(s)&oldid=1495762"