hybE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HybE

Synonyms

hydrogenase 2-specific chaperone[1], B2992[2][1], HybE[2][1] , ECK2986, JW2960, b2992

Product description

hydrogenase 2-specific chaperone[2][3]

Function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0070678

preprotein binding

PMID:12914940[5]

IPI: Inferred from Physical Interaction

UniProtKB:P0ACE0

F

Seeded from EcoCyc (v14.0)

complete

GO:0070678

preprotein binding

PMID:12914940[5]

IPI: Inferred from Physical Interaction

UniProtKB:P69741

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

nrfA

PMID:16606699[6]

Experiment(s):EBI-1144509

Protein

purC

PMID:16606699[6]

Experiment(s):EBI-1144509

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1144509

Protein

hybO

PMID:15690043[7]

Experiment(s):EBI-882521

Protein

hybO

PMID:19402753[8]

MALDI(Z-score):17.053160

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MTEEIAGFQT SPKAQVQAAF EEIARRSMHD LSFLHPSMPV YVSDFTLFEG QWTGCVITPW
MLSAVIFPGP DQLWPLRKVS EKIGLQLPYG TMTFTVGELD GVSQYLSCSL MSPLSHSMSI
EEGQRLTDDC ARMILSLPVT NPDVPHAGRR ALLFGRRSGE NA
Length

162

Mol. Wt

17.963 kDa

pI

5.3 (calculated)

Extinction coefficient

20,970 - 21,345 (calc based on 3 Y, 3 W, and 3 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Domain

8..158

PF11939 Protein of unknown function (DUF3457)

PMID:19920124[9]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hybE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130892

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947483

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009824

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AAN1

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11803

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11803

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947483

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001737

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1751

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Dubini, A & Sargent, F (2003) Assembly of Tat-dependent [NiFe] hydrogenases: identification of precursor-binding accessory proteins. FEBS Lett. 549 141-6 PubMed
  6. ↑ 6.0 6.1 6.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  8. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

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