hupB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HupB

Synonyms

HU, DNA-binding transcriptional regulator, beta subunit[1], B0440[2][1], DpeA[2][1], HopD[2][1], DbhB[2][1], HupB[2][1] , dpeA, ECK0434, hopD, JW0430, b0440

Product description

DNA-binding protein HU-β, NS1 (HU-1)[2]; Transcriptional dual regulator HU-β, NS1 (HU-1)[3];

Component of HU Transcriptional dual regulator[3]

Histone-like protein HU-beta, HU-1[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000119

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010992

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020816

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

Contributes to

GO:0003677

DNA binding

PMID:10551881[5]

IDA: Inferred from Direct Assay

F

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of HU Transcriptional dual regulator

could be indirect

Protein

hsdM

PMID:15690043[6]

Experiment(s):EBI-886990

Protein

malP

PMID:15690043[6]

Experiment(s):EBI-886990, EBI-884415

Protein

malQ

PMID:15690043[6]

Experiment(s):EBI-886990, EBI-884415

Protein

polA

PMID:15690043[6]

Experiment(s):EBI-886990, EBI-892889, EBI-884415

Protein

fis

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

ihfA

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

skp

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

hns

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

rplC

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

rpoA

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

rpsG

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

seqA

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

rdgC

PMID:15690043[6]

Experiment(s):EBI-884415

Protein

dnaE

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplC

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

yghW

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

nfnB

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplI

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

nuoE

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

htpG

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rpsI

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplS

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rhlE

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rpsD

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

greA

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplB

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

sdhA

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rpsG

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

uspG

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplA

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

yebG

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

pepD

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplU

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

vsr

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rplQ

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

dnaK

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

slyD

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

ydcP

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

rpsM

PMID:16606699[7]

Experiment(s):EBI-1136666

Protein

ihfB

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):2.338232

Protein

skp

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

fis

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

hns

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

rpoA

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

malQ

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):26.284388

Protein

hsdM

PMID:19402753[8]

MALDI(Z-score):23.699803

Protein

malP

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):24.332948

Protein

polA

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):14.532702

Protein

rdgC

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

ihfA

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

hupA

PMID:19402753[8]

LCMS(ID Probability):99.6 MALDI(Z-score):7.883297

Protein

seqA

PMID:19402753[8]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNKSQLIDKI AAGADISKAA AGRALDAIIA SVTESLKEGD DVALVGFGTF AVKERAARTG
RNPQTGKEIT IAAAKVPSFR AGKALKDAVN
Length

90

Mol. Wt

9.225 kDa

pI

10.1 (calculated)

Extinction coefficient

0 (calc based on 0 Y, 0 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

1..90

PF00216 Bacterial DNA-binding protein

PMID:19920124[9]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hupB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128425

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949095

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001527

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ACF4

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10467

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10467

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949095

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000460

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0462

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Azam, TA & Ishihama, A (1999) Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity. J. Biol. Chem. 274 33105-13 PubMed
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  7. 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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