hofB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HofB

Synonyms

conserved protein with nucleoside triphosphate hydrolase domain[1], B0107[2][1], HopB[2][1], HofB[2][1] , ECK0106, hopB, JW0103, b0107

Product description

protein involved in plasmid replication[2][3]

Homologous to PilB of Pseudomonas aeruginosa; function not established, insertion mutation gives no phenotype[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001482

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007831

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001482

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001482

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007831

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0017111

nucleoside-triphosphatase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

purB

PMID:16606699[5]

Experiment(s):EBI-1135581

Protein

dnaK

PMID:16606699[5]

Experiment(s):EBI-1135581

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1135581

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNIPQLTALC LRYHGVLLDA SEEVVHVAVV DAPSHELLDA LHFATTKRIE ITCWTRQQME
GHASRTQQTL PVAVQEKHQP KAELLTRTLQ SALEQRASDI HIEPADNAYR IRLRIDGVLH
PLPDVSPDAG VALTARLKVL GNLDIAEHRL PQDGQFTVEL AGNAVSFRIA TLPCRGGEKV
VLRLLQQVGQ ALDVNTLGMQ PLQLADFAHA LQQPQGLVLV TGPTGSGKTV TLYSALQKLN
TADINICSVE DPVEIPIAGL NQTQIHPRAG LTFQGVLRAL LRQDPDVIMI GEIRDGETAE
IAIKAAQTGH LVLSTLHTNS TCETLVRLQQ MGVARWMLSS ALTLVIAQRL VRKLCPHCRR
QQGEPIHIPD NVWPSPLPHW QAPGCVHCYH GFYGRTALFE VLPITPVIRQ LISANTDVES
LETHARQAGM RTLFENGCLA VEQGLTTFEE LIRVLGMPHG E
Length

461

Mol. Wt

50.614 kDa

pI

6.7 (calculated)

Extinction coefficient

29,450 - 30,700 (calc based on 5 Y, 4 W, and 10 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

76..354

PF00437 Type II/IV secretion system protein

PMID:19920124[6]

Domain

6..73

PF05157 GSPII_E N-terminal domain

PMID:19920124[6]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hofB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128100

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947481

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000370

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P36645

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12106

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12106

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947481

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002011

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2030

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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