grxD:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YdhD

Synonyms

conserved protein[1], B1654[2][1], YdhD[2][1], GrxD[2][1], Grx4[2][1] , ECK1650, JW1646, ydhD, b1654

Product description

glutaredoxin 4[2][3]

Monothiol glutaredoxin Grx4, with CxxS motif; substrate for thioredoxin reductase; essential gene[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0009055

electron carrier activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002109

F

Seeded from EcoCyc (v14.0)

complete

GO:0015035

protein disulfide oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002109

F

Seeded from EcoCyc (v14.0)

complete

GO:0022900

electron transport chain

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0249

P

Seeded from EcoCyc (v14.0)

complete

GO:0045454

cell redox homeostasis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002109

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

selD

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rplE

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

nuoE

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rplB

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

slyD

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

cysQ

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

nadE

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

yeeT

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

mreB

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

nrdI

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rplO

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rpsC

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rpsB

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

fur

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

napC

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

csrA

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

rpsD

PMID:16606699[5]

Experiment(s):EBI-1140371

Protein

bolA

PMID:19402753[6]

LCMS(ID Probability):99.6 MALDI(Z-score):9.486753

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSTTIEKIQR QIAENPILLY MKGSPKLPSC GFSAQAVQAL AACGERFAYV DILQNPDIRA
ELPKYANWPT FPQLWVDGEL VGGCDIVIEM YQRGELQQLI KETAAKYKSE EPDAE
Length

115

Mol. Wt

12.878 kDa

pI

4.5 (calculated)

Extinction coefficient

18,450 - 18,825 (calc based on 5 Y, 2 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

17..81

PF00462 Glutaredoxin

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=grxD taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129612

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946169

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0005527

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AC69

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12181

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12181

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946169

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002074

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2098

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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