gatR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GatR

Synonyms

B2087[1], GatR_1[1], GatR[1], split galactitol utilization operon repressor, fragment 1[1], B2090[1], split galactitol utilization operon repressor, fragment 2[1] , ECK2083, JW2074, JW5340, b4498

Product description

Note that this is a pseudogene in K12 strains.

negative DNA-binding transcriptional regulator of galactitol metabolism[1][2]; GatR_2[1][2];

Component of GatR transcriptional repressor[1][2]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001034

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018356

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001034

C

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018356

C

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001034

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018356

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of GatR transcriptional repressor

could be indirect

Protein

ptrA

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

dnaK

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

nadE

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

groL

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

lacZ

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

fabZ

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

tatE

PMID:16606699[3]

Experiment(s):EBI-1141888

Protein

tktB

PMID:16606699[3]

Experiment(s):EBI-1141888

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name

E. coli B strain REL606 GatR GenBank record ACT39674.1

Sequence
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQE
VGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKD
ITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAV
LDSSKFNRRGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV
Length

257

Mol. Wt

27.726 kDa

pI

7.5 (calculated)

Extinction coefficient

1,490 - 1,615 (calc based on 1 Y, W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

83..238

PF00455 Bacterial regulatory proteins, deoR family

PMID:19920124[4]

Domain

8..63

PF08220 DeoR-like helix-turn-helix domain

PMID:19920124[4]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=gatR_2 taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

ASAP

ASAP:ABE-0006921

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:2847672

Escherichia coli str. K-12 substr. MG1655

ASAP (EcoliWiki Page)

[https://asap.ahabs.wisc.edu/asap/feature_info.php?FeatureID=ABE-0006921 ASAP:ABE-0006921]

Escherichia coli str. K-12 substr. MG1655

ASAP (EcoliWiki Page)

ASAP:ABE-0285099

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P36930

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12162

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:2847672

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12162

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002058

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. 2.0 2.1 2.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  4. 4.0 4.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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