garR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GarR

Synonyms

tartronate semialdehyde reductase[1], B3125[2][1], YhaE[2][1], GarR[2][1] , ECK3113, JW5526, yhaE, b3125

Product description

TSA- Tartronate semialdehyde reductase, glycerate- or galactarate-inducible[3]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0004616

phosphogluconate dehydrogenase (decarboxylating) activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006115

F

Seeded from EcoCyc (v14.0)

complete

GO:0004616

phosphogluconate dehydrogenase (decarboxylating) activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006183

F

Seeded from EcoCyc (v14.0)

complete

GO:0005488

binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

Seeded from EcoCyc (v14.0)

complete

GO:0006098

pentose-phosphate shunt

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006115

P

Seeded from EcoCyc (v14.0)

complete

GO:0006098

pentose-phosphate shunt

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006183

P

Seeded from EcoCyc (v14.0)

complete

GO:0006573

valine metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002204

P

Seeded from EcoCyc (v14.0)

complete

GO:0008442

3-hydroxyisobutyrate dehydrogenase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002204

F

Seeded from EcoCyc (v14.0)

complete

GO:0008679

2-hydroxy-3-oxopropionate reductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006398

F

Seeded from EcoCyc (v14.0)

complete

GO:0008679

2-hydroxy-3-oxopropionate reductase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.1.1.60

F

Seeded from EcoCyc (v14.0)

complete

GO:0046487

glyoxylate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006398

P

Seeded from EcoCyc (v14.0)

complete

GO:0050662

coenzyme binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013328

F

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002204

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006115

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006183

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006398

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MIDMTMKVGF IGLGIMGKPM SKNLLKAGYS LVVADRNPEA IADVIAAGAE TASTAKAIAE
QCDVIITMLP NSPHVKEVAL GENGIIEGAK PGTVLIDMSS IAPLASREIS EALKAKGIDM
LDAPVSGGEP KAIDGTLSVM VGGDKAIFDK YYDLMKAMAG SVVHTGEIGA GNVTKLANQV
IVALNIAAMS EALTLATKAG VNPDLVYQAI RGGLAGSTVL DAKAPMVMDR NFKPGFRIDL
HIKDLANALD TSHGVGAQLP LTAAVMEMMQ ALRADGLGTA DHSALACYYE KLAKVEVTR
Length

299

Mol. Wt

31.019 kDa

pI

5.4 (calculated)

Extinction coefficient

8,940 - 9,190 (calc based on 6 Y, 0 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

1..162

PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase

PMID:19920124[4]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=garR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:145698315

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947631

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010273

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABQ2

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11176

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11176

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947631

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001158

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1163

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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